A study of thyroid profile abnormalities in vitiligo patients in tertiary care center of South India, in Telangana

Authors

  • Sushmalatha B. Department of DVL, Mamata Medical College, Khammam, Telangana, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20192631

Keywords:

Thyroid, Thyroid profile, Vitiligo, Auto immune

Abstract

Background: Several autoimmune conditions are associated with vitiligo. But thyroid is most common cause. We under took the study for the incidence of association of thyroid abnormalities involving in patients of vitiligo. The present study is conducted to know the incidence of thyroid profile abnormalities in various morphological forms of vitiligo.

Methods: The present study was conducted on 53 patients of clinically diagnosed cases of vitiligo in the outpatients department of DVL of Mamata General Hospital for a period of 1 year 2018 January to 2019 January. 53 patients of age sex matched patients with other dermatosis excluding vitiligo are randomly designed as controls. Investigations were carried out in all patients of vitiligo like routine, specific like thyroid profile (T3, T4, TSH profile).

Results: The presence study showing female to male ratio is 1:3:1 thyroid function abnormalities found in 33.96% of patients compared to 7.54% controls.

Conclusions: In present study has shown that autoimmune thyroid diseases both in the form of hypothyroid, hyper thyroidism are frequently associated with vitiligo patients.

Author Biography

Sushmalatha B., Department of DVL, Mamata Medical College, Khammam, Telangana, India

Assistant Professor, Department of DVL

Mamata Medical College, Khammam

Telangana- 507001

References

Singh G, Ansari Z, Dwivedi RN. Vitiligo in ancient Indian medicine. Arch Dermatol. 1974;109(6):913.

Porter J, Beuf AH, Nordlund JJ, Lerner AB. Psychological reaction to chronic skin disorders: a study of patients with vitiligo. General Hospital Psychiatry. 1979;1(1):73-7.

Koranne RK, Sachdeva KG. Vitiligo. Int J Dermatol. 1988;27:676-81.

Lerner AB, Nordlund JJ. Vitiligo: What is it? Is it important? JAMA. 1978;239(12):1183-7.

Nair BK. Vitiligo‐a retrospect. Int J Dermatol. 1978;17(9):755-7.

Halder RM, Grimes PE, Cowan CA, Enterline JA, Chakrabarti SG, Kenney Jr JA. Childhood vitiligo. J Am Acad Dermatol. 1987;16(5):948-54.

Barsky S, Knapp DP, Levine M, Schuller-Goldman S. Vitiligo in a black population. Arch Dermatol. 1979;115(2):225.

Hegedüs L, Heidenheim M, Gervil M, Hjalgrim H, Høier-Madsen M. High frequency of thyroid dysfunction in patients with vitiligo. Acta Dermato-Venereologica. 1994;74(2):120-3.

Cunliffe WJ, Hall R, Newell DJ, Stevenson CJ. Vitiligo, thyroid disease and autoimmunity. Br J Dermatol. 1968;80(3):135-9.

Dervis E, Acbay O, Barut G, Karaoglu A, Ersoy L. Association of vitiligo, morphea, and Hashimoto's thyroiditis. Int J Dermatol. 2004;43(3):236-7.

Ochi Y, Degroot LJ. Vitiligo in Graves' disease. Ann Internal Med. 1969;71(5):935-40.

Kurtev A, Dourmishev AL. Thyroid function and autoimmunity in children and adolescents with vitiligo. J Eur Acad Dermatol Venereol. 2004;18(1):109-11.

Ghosh KK, Pal SK, Benarjee PK. Thyroid function in vitiligo. Clinica Chemica Acta. 1980;106:331-2.

Arora NV, Shankar V, Chaudhary SD, Nagpal RK. Triiodothyronine, thyroxine and thyrotropin levels in vitiligo. Indian J Dermatol Venereol Leprol. 1990;56(4):299-300.

Downloads

Published

2019-07-24

Issue

Section

Original Research Articles