DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20191761

Study of the clinical pattern of contact dermatitis over the face and its correlation with patch testing

Saumya Goel, Vinma H. Shetty, Hafsa Eram, Amita Murali Babu

Abstract


Background: Contact dermatitis (CD) is an altered state of reactivity; occur due to direct contact with noxious agents in our environment. Face is a very common site for CD.

Methods: Prospective hospital based study was conducted at A. J. Institute of Medical Sciences, Mangalore from June 2018 to November 2018. Fifty cases aged above 18 years with suspected allergic contact dermatitis (ACD) over face who gave written informed consent were enrolled. A complete history was taken and detailed clinical examination was done. Patch testing was done over the back in all patients which was removed after 48 hours and positive result was recorded based on the recommendation of the international Contact Dermatitis Research Group (ICDRG).

Results: The most common clinical pattern observed was pigmented contact dermatitis(PCD) (70%), followed by irritation (6%), acneiform eruptions (5%) and contact urticaria (2%). Out of 50 patients, 20 patients developed CD to fragrances and perfumes. 14 patients developed to soaps and shampoos. On patch testing, most common allergen in fragrances/perfumes was fragrance mix (52.9%). In soaps and shampoos it was triclosan (68.4%), parabens (31.5%). Sesquiterpene lactone in parthenium plant (4%), Paraphenylenediamine in hair dye (8%). In face creams were gallate mix and cetrimide among metals, nickel and chromium (6%). In case of kumkum it was paraphenylenediamine (4%).

Conclusions: Amongst the various patterns of contact dermatitis, PCD to cosmetics, fragrances and daily care products was most common pattern observed and the main allergens were triclosan, fragrance mix and balsum of Peru.


Keywords


Contact dermatitis, Face, Patch test

Full Text:

PDF

References


Lachapelle JM. Historical Aspects. In: Rycroft RJG, Menne T, Frosch PJ, Lepoittenevin JP, eds. Textbook of Contact Dermatitis, 3rd ed. Berlin: Springer; 2001: 3-9.

Beck MH, Wilkinson SM. Contact dermatitis: Allergic. In: Tony Burns, Stephen Breathnach, Christopher Griffiths et al. Rook’s text book of Dermatology. 7th ed. Blackwell sciences; 2004: 20.

Sharma VK, Sethuram G, Garg T, Verma KK. Patch testing with the ISS in New Delhi. Contact dermatitis. 2004;51:319-21.

Narendra G, Srinivas CR. Patch testing with Indian standard series. Indian J Dermatol Venereol Leprol. 2002;68:281-2.

Kumar P, Paulose Ra. Patch Testing in Suspected Allergic Contact Dermatitis to Cosmetics. Dermatol Res Prac. 2014;2014:695387.

Bolognia J, Jorizzo J, Schaffer J. Dermatology. Elsevier Saunders, Philadelphia, PA; 2012.

Fonacier L, Bernstein DI, Pacheco K, Holness DL, Blessing-Moore J, Khan D, et al. Contact dermatitis: a practice parameter-update 2015. J Allergy Clin Immunol Pract. 2015;3:S1–S39.

Johansen JD, Aalto-Korte K, Agner T, Andersen KE, Bircher A, Bruze M, et al. European Society of Contact Dermatitis guideline for diagnostic patch testing—recommendations on best practice. Contact Dermatitis. 2015;73:195–221.

Laguna C, de la Cuadra J, Martín-González B, Zaragoza V, Martínez-Casimiro L, Alegre V. Allergic contact dermatitis to cosmetics. Actas Dermosifiliogr. 2009;100:53-60.

Duarte I, Campos-Lage A. Frequency of dermatoses associated with cosmetics. Contact dermatitis. 2007;56:211.

Kohl L, Blondeel A, Song M. Allergic contact dermatitis from cosmetics. Dermatology. 2002;204:334.

de Groot AC, Bruynzeel DP, Bos JD, van der Meeren HL, van Joost T, Jagtman BA, et al. The allergens in cosmetics. Arch Dermatol. 1988;124:1525.

Davies RF, Johnston GA. New and emerging cosmetic allergens. Clin Dermatol. 2011;29:311–5.

Hamilton T, de Gannes GC. Allergic contact dermatitis to preservatives and fragrances in cosmetics. Skin Therapy Lett. 2011;16:1–4.

Frosch PJ, Rastogi SC, Pirker C, Brinkmeier T, Andersen KE, Bruze M, et al. Patch testing with a new fragrance mix—reactivity to the individual constituents and chemical detection in relevant cosmetic products. Contact Dermatitis. 2005;52:216–25.

Salam TN, Fowler JF Jr. Balsam-related systemic contact dermatitis. J Am Acad Dermatol. 2001;45:377–81.

Castanedo-Tardana MP, Zug KA. Methylisothiazolinone. Dermatitis. 2013;24:2–6.

Rietschel RL, Fowler JF. Allergy to preservatives and vehicles in cosmetics and toiletries. In: Rietschel RL, Fowler JF, editors. Fisher’s Contact Dermatitis. 5th edition. Philadelphia, Pa, USA: Lippincott Williams & Wilkins; 2001: 211–259.

Mehta SS, Reddy BSN. Pattern of cosmetic sensitivity in Indian patients. Contact Dermatitis. 2001;45(5):292–3.

Bhutani LK, Rao DS. Photocontact dermatitis caused by Parthenium hysterophorous. Dermatologica. 1978;157:206-9.

Goh CL, Kozuka T. Pigmented contact dermatitis from 'kumkum'. Clin Exp Dermatol. 1986;11:603-6.

Kumar AS, Pandhi RK, Bhutani LK. Bindi dermatoses. Int J Dermatol 1986;25:434-5.