Omalizumab in chronic spontaneous urticaria

Authors

  • Ramesh A. Department of Dermatology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu
  • Sampath V. Department of Dermatology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu
  • Dhanalakshmi U. R. Department of Dermatology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu
  • Vinitha Kumari G. Department of Dermatology, Madras Medical College, Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20183170

Keywords:

Chronic spontaneous urticaria, Urticaria activity score, Omalizumab

Abstract

Background: Chronic spontaneous urticaria is a common skin disorder affecting 0.5 to 1% of people in the general population. There are a variety of treatment options available without much successful outcome. Omalizumab is a novel treatment option which can be used in the treatment of chronic spontaneous urticaria. The aim of our study is to assess the efficacy of omalizumab in chronic spontaneous urticaria.

Methods: A retrospective analysis of data of 10 patients with chronic spontaneous urticaria who were treated with three doses of omalizumab in our institution. Doses were given at monthly intervals for 3 months and they were followed for another 6 months. Response was assessed using urticaria activity score.

Results: 70% of patients had well controlled urticaria with 3 doses of omalizumab by the end of 9 months.

Conclusions:Omalizumab is a safe and effective treatment option in the management of chronic spontaneous urticaria. 

 

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Published

2018-07-24

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Original Research Articles