Gianotti-Crosti syndrome: exanthema following a vaccination

Authors

  • Suni C. Widjaya Department of Dermatology and Venerology, Regional General Hospital R. Soedjono Selong, East Lombok, West Nusa Tenggara, Indonesia
  • Lysa Mariam Department of Dermatology and Venerology, Regional General Hospital R. Soedjono Selong, East Lombok, West Nusa Tenggara, Indonesia

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20220500

Keywords:

Gianotti-crosti syndrome, Exanthema, Vaccination

Abstract

Gianotti-Crosti syndrome (GCS) is a benign skin disorder characterized by self-limiting acute exanthema. Commonly preceding with the infection of viruses or bacteria and vaccinations. Usually affects children aged 1-6 years and is associated with atopic disease. The exact of GCS incidence is unknown, although several countries in the world have been reported GCS cases. Vaccine-induced GCS cases are infrequently reported. The diagnosis can be made clinically based on clinical features and vaccination history. Treatment is generally symptomatic. Education about GCS is important to prevent over-treatment and avoidance of vaccination in the future. We reported a 9-month-old baby with symmetrical bilateral monomorphic multiple dome-shaped papules lesions on the extremities two days following vaccination.

Author Biographies

Suni C. Widjaya, Department of Dermatology and Venerology, Regional General Hospital R. Soedjono Selong, East Lombok, West Nusa Tenggara, Indonesia

Department of Dermatology and Venerology Regional General Hospital R. Soedjono Selong, East Lombok, West Nusa Tenggara

Lysa Mariam, Department of Dermatology and Venerology, Regional General Hospital R. Soedjono Selong, East Lombok, West Nusa Tenggara, Indonesia

Department of Dermatology and Venerology Regional General Hospital R. Soedjono Selong, East Lombok, West Nusa Tenggara

References

Oza VS, Mathes EF. Viral diseases. In: Kang S, Amagai M, Bruckner AL, Enk AH, Morgolis DJ, McMichael AJ, et al, editors. Fitzpatrick’s Dermatology 9th Edition. McGraw-Hill Education. 2019;3002-4.

Snowden J, Rice AS, O’Shea NE. Papular acrodermatitis. StatPearls. Treasure Island (FL): StatPearls Publishing. 2021.

Craig-Muller SA, Elston, DM. In: Elston DM, Windle ML, Schwartz RA, et al. Gianotti-Crosti syndrome. Medscape. 2020.

Dhaheri HS, Kaabi AA, Hamo YK, Kaabi AA, Kaabi SA, Tatari HA. Unusual presentation of Gianotti-Crosti syndrome due to Epstein-bar virus infection. Case Rep Dermatol Med. 2016;1017524.

Assaf J, Stephan F, Zeinaty P, Tomb R. A case of recurrent vaccine-triggered Gianotti-Crosti syndrome. Future Sci OA. 2021;7(6).

Alexandre S, Constante AR, Abdula Z, Santos S. Just one more rash? BMJ Case Reports CP. 2019;12:bcr-2018-228751.

Shah KN. In: James WD, Vinson RP, Perry V, Schwartz RA, editors. Dermatologic manifestation of Gianotti-Crosti syndrome. Medscape. 2020.

Llanora GV, Tay CM, Bever HP. Gianotti-Crosti syndrome: case report of a pruritic acral exanthema in a child. Asia Pac Allergy. 2012;2(3):223-6.

AlSabbagh MM, Kassim AK. Gianotti-Crosti syndrome-the first case report from Bahrain: a rare presentation following vaccinations. Journal of Dermatology and Dermatologic Surgery. 2016;20(1):67-70.

Marcassi AP, Seize MB. Atypical Gianotti-Crosti syndrome. An Bras Dermatol. 2018;93(2):265-7.

Oka M. Simultaneous development of Gianotti-Crossti syndrome and erythema multiforme following second dose of measles-rubella vaccine. Acta Derm Venereol. 2021;101(4):adv00438.

Caltabino R, Vecchio GM, Pasquale RD, Loreto C, Leonardi R, Vasquez E. Human β-defensin 4 expression in Gianotti-Crosti syndrome. Acta Dermatovenerol Croat. 2013;21(1):43-7.

Downloads

Published

2022-02-24

Issue

Section

Case Reports