Clinicoepidemiological study of chronic urticaria in a government tertiary care centre in South India


  • C. Vijayabhaskar Department of Dermatology, Madras Medical College and Rajiv Gandhi Government General Hospital, Chennai, Tamil Nadu, India
  • S. Venkatesan Department of Dermatology, Government Omanthurar Medical College, Chennai, Tamil Nadu, India



Absolute eosinophil count, Chronic urticaria, Comorbidities, Presentation


Background: According to the consensus statement 2017, urticaria is a common skin condition with a lifetime prevalence of 22% and point prevalence of 1%. This study aims to study the clinico epidemiological presentation of chronic urticaria in patients attending a govt. tertiary care center and to assess absolute eosinophil count.

Methods: This observational study was conducted in patients with chronic urticaria presenting to the outpatient clinic of Dermatology department. Patients details including demographics, clinical manifestations, investigations, associated comorbidities, and therapeutic were collected.

Results: Chronic urticaria is commonly present in females-appears commonly in 4th decade but patients present to tertiary care center only in 5th decade-duration was less than 1 year in males, but it was equally between 1-2 and 2-4 years in females. Ear, nose, throat and dental involvement are negligible and common comorbidities are diabetes mellitus, hypertension and hypothyroidism. 42% of patients present with more than normal absolute eosinophil count.

Conclusions: Chronic urticaria was common in females with 5th decade being the common age of presentation to the tertiary care center and 4th decade being the common age of disease onset. Paediatric population is less affected. Common comorbidities like diabetes mellitus, hypertension and hypothyroidism are to be ruled out. Raised absolute eosinophil count has to be looked for.


Zuberbier T, Balke M, Worm M, Edenharter G, Maurer M. Epidemiology of urticaria: a representative cross‐sectional population survey. Clini Experiment Dermatol. 2010;35(8):869-73.

Fairbairn S. Current opinion in allergy and clinical immunology. Curr Opinion Aller Clini Immunol. 2018;18(3):167.

Sugiyama A, Nishie H, Takeuchi S, Yoshinari M, Furue M. Hashimoto's disease is a frequent comorbidity and an exacerbating factor of chronic spontaneous urticaria. Allergol Immunopathol. 2015;43(3):249-53.

Lindelöf B, Sigurgeirsson B, Wahlgren CF, Eklund G. Chronic urticaria and cancer: an epidemiological study of 1155 patients. Brit J Dermatol. 1990;123(4):453-6.

Zhong H, Song Z, Chen W, Li H, He L, Gao T, et al. Chronic urticaria in C hinese population: a hospital‐based multicenter epidemiological study. Allergy. 2014;69(3):359-64.

Balp MM, Weller K, Carboni V, Chirilov A, Papavassilis C, Severin T, et al. Prevalence and clinical characteristics of chronic spontaneous urticaria in pediatric patients. Pediatr Allergy Immunol. 2018;29(6):630-6.

Zuberbier T, Althaus C, Chantraine-Hess S, Czarnetzki BM. Prevalence of cholinergic urticaria in young adults. J Am Acad Dermatol. 1994;31(6):978-81.

Katsarou‐Katsari A, Makris M, Lagogianni E, Gregoriou S, Theoharides T, Kalogeromitros D. Clinical features and natural history of acquired cold urticaria in a tertiary referral hospital: a 10‐year prospective study. J Europ Acad Dermatol Venereol. 2008;22(12):1405-11.

Lapi F, Cassano N, Pegoraro V, Cataldo N, Heiman F, Cricelli I, et al. Epidemiology of chronic spontaneous urticaria: results from a nationwide, population‐based study in Italy. Brit J Dermatol. 2016;174(5):996-1004.

Kim BR, Yang S, Choi JW, Choi CW, Youn SW. Epidemiology and comorbidities of patients with chronic urticaria in Korea: A nationwide population‐based study. J Dermatol. 2018;45(1):10-6.






Original Research Articles