Clinical and histopathological profile of benign appendageal tumours of skin: a descriptive study from Andhra Pradesh


  • Prathyusha Pathakamuri Department of Dermatology, Government General Hospital, Kadapa, Andhra Pradesh, India
  • Venkateswaramma Begari Department of Dermatology, Navodaya Medical College, Raichur, Karnataka, India
  • Anant A. Takalkar Department of Community Medicine, MIMSR Medical College, Latur, Maharashtra, India



Skin appendageal, Clinical profile, Histopathological findings


Background: Skin adnexal tumors are those neoplasms that arise from pilosebaceous units, eccrine sweat glands or apocrine sweat glands. Vast majority of appendageal tumors are benign and most of the benign skin adnexal tumors are asymptomatic papules or nodules and often difficult to diagnose clinically. The objective of the study was to study the clinical and histological features suggestive of benign skin appendageal tumors.

Methods: This is a descriptive observational study conducted among 50 patients presenting with clinical features suggestive of benign skin appendageal tumors attending at outpatient department of DVL, Kurnool medical college/ GGH, Kurnool between January 2016 to June 2017.

Results: The highest age incidence was in the age group of 21-30 years- 24 cases (48%). The commonest tumors in this study were eccrine gland tumors i.e 43 cases (86%). Syringomas were the commonest tumors (38 cases, 76%). Commonest presenting lesion was papule (82%). Commonest site is face (94%).

Conclusions: The commonest tumors recorded were eccrine gland tumors (86%). Syringomas constitute the largest group (76%) followed by trichoepitheliomas (6%). The highest age incidences was in 3rd decade (48%), followed by 4th decade (42%).


Ahmed TSS, Priore JD, Seykora JT. Tumors of the epidermal appendages. In: Elder DE, Elenitsas R, Johnson BL, Murphy GF, Xu X, editors. Lever’s Histopathology of skin. 10th ed. Southasian: Lippincott Williams Wilkins; 2009: 851-909

Stantaylor R, Perone JB, Kaddu S, Kerl H. Appendage tumors and hamartomas of skin, in Fitzpatrick’s Dermatology in General Medicine. In: Wolff K, Goldsmith L, Katz S, Gilchrest BA, Paller AS, Leffell DS, eds. 7th edition. New York, NY: USA: MC Graw Hill; 2008: 1068-1087.

Penneys HS. Immunohistochemistry of adnexal neoplasms. J Cutaneous Pathol. 1984;11(5):357-64.

Mackie RM, Calonje E. Tumors of the Skin Appendages. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rooks Textbook of Dermatology. 7th ed. London: Blackwell Publishing Company; 2004: 1-34.

Khandpur S, Ramam M. Skin Tumors. In: Valia RG, Valia AR, editors. IADVL Text book of Dermatology. 3rd ed. Mumbai: Bhalani Publishing House; 2008: 1438-1475.

Samaila MO. Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med. 2008;7:6-10.

Kala PS, Azad S, Kumar R, Thakur B, Bis JS. Skin Appendageal Tumors: An Institutional Experience from Northern India. National J Laboratory Med. 2018;7(4):01-8.

Kaur K, Gupta K, Hemrajani D, Yadav A, Mangal K. Histopathological analysis of skin adnexal tumours: A three year study of 110 Cases at a tertiary care center. Indian J Dermatol. 2017;62:400-6.

El Ochi MR, Boudhas A, Allaoui M, Rharrassi I, Chahdi H, Bouzidi AA, et al. Adnexal skin tumors: pathological study of 96 cases. Pan Afr Med J. 2015;20:389.

Rajalakshmi V, Selvakumar S, Rajeswari K, Meenakshisundaram K, Veena G, Ramachandran P. Case series of skin adnexal tumours. J Clin Diagn Res. 2014;8(9):7-10.

Radhika K, Phaneendra BV, Rukmangadha N, Reddy MK. A study of biopsy confirmed skin adnexal tumours: experience at a tertiary care teaching hospital. J Clin Sci Res. 2013;2(1):132-8.

Nair PS. A clinicopathological study of skin appendageal tumours. Indian J Dermatol Venereol Leprol. 2008;74(5):550.

Sharma A, Paricharak DG, Nigam JS, Rewri S, Soni PB, Omhare A, et al. Histopathological study of skin adnexal tumours-institutional study in South India. J Skin Cancer. 2014;4:1-4.

Saha A, Das NK, Gharami RC, Chowdhury SN, Datta PK. A clinico-histopathological study of appendageal skin tumors, affecting head and neck region in patients attending the dermatology opd of a tertiary care centre in eastern India. Indian J Dermatol. 2011;56(1):33-6.






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