DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20194666

Study of cutaneous manifestations in chronic kidney disease patients on maintenance hemodialysis at a tertiary care centre

Kirankanth Vudayana, Vidyasagar Korla, Dilipchandra Chintada, Jami Vijaya Shree

Abstract


Background: Chronic kidney disease (CKD) is a progressive loss of kidney function over a period of months or years through five stages, presents with various cutaneous manifestations regardless of its aetiology. Patients of CKD disease on hemodialysis treatment which prolong the life expectancy and can also produce skin lesions. Skin changes described in patients with chronic renal disease are also found in patients with renal failure undergoing treatment with either peritoneal dialysis or hemodialysis. High percentage of patients receiving dialysis complains of pruritus that may be severe, in some instances the pruritus worsens with dialysis. The aims of the present study were to study the pattern of cutaneous lesions in patients with chronic kidney disease and to determine the incidence of skin manifestations specific to and associated with CKD.

Methods: Hundred patients of CKD on MHD with cutaneous manifestations attending skin outpatient department, nephrology out-patient department, dialysis center and patients admitted in medical wards were included in the study.

Results: The common cutaneous manifestations were xerosis 91%, pallor 78% and pruritus 69%. Nail manifestations include onycholysis 37% and half and half nails 33%. Hair manifestations in 24% patients.

Conclusions: Most common cutaneous manifestation was xerosis, followed by pallor. Most common nail manifestation was onyholysis.


Keywords


CKD on MHD, Cutaneous manifestations, Pruritis, Xerosis, Pallor, Onycholysis, Half and half nail

Full Text:

PDF

References


Kher V. End-stage renal disease in developing countries. Kidney Int. 2002;62(1):350-62.

Pastan S, Bailey J. Medical progress: dialysis therapy. New England J Med. 1998;338(20):1428-37.

Hajheydari Z, Makhlough A. Cutaneous and mucosal manifestations in patients on maintenance hemodialysis: a study of 101 patients in Sari, Iran. Iran J Kidney Dis. 2008;2(2):86-90.

Nunley JR. Dermatologic manifestations of renal disease. eMed. 2002: 550.

Pico MR, Lugo-Somolinos A. Cutaneous alterations in patients with chronic renal failure. Int J Dermatol. 1992;31:860-3.

Guptha AK, Guptha MA, Cardella CJ, Haberman HF. Cutaneous associations of chronic renal failure and dialysis. Int J Dermatol. 1986;25:498-504.

Udayakumar P, Balasubramanian S, Ramalingam KS, Lakshmi C, Srinivas CR, Mathew AC. Cutaneous manifestations in patients with chronic renal failure on hemodialysis. Indian J Dermatol Venereol Lep-rol. 2006;72(2):119-25.

Morton CA, Lafferty M, Hau C, Henderson I, Jones M, Lowe JG. Pruritus and skin hydration during dialysis. Nephron Dial Transplant. 1996;11:2031-6.

Tawade N, Gokhale BB. Dermatologic manifestation of chronic renal failure. Indian J Dermatol Venereol Lep-rol. 1996;62:155-6.

Yaghubi R, Niloufer S, Latifee SM. Cutaneous manifestations of end stage renal diseases under hemodialy-sis. Iran J Dermatol. 2002;5:29-34.

Naderi N, Mahadevi-Mazedeh M, FIrouz A, Seraj MH. Cutaneous manifestations of end stage renal diseases under hemodialysis in hemodialysis ward at Imam Khomeini hospital in Tehran in 2003. Iran J Dermatol. 2005;6:489-95.

Deshmuk SP, Sharma YK, Dash K, Chaudhari NC, Deo KS. Clinico-epidemiological study of manifestations in patients of chronic renal failure on hemodialysis. Indian Dermatol Online J. 2013;4(1):18-21.