Treatment outcome of acne vulgaris with topical application of clindamycin gel and benzoyl peroxide gel as supplementary files
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20194681Keywords:
Acne vulgaris, Adolescents, Cindamycin, RegimensAbstract
Background: Acne vulgaris is one of the commonest inflammatory skin disorders. It also has a psychosocial impact on patients, specially known in adolescents and hence needs effective treatment. The objectives of the study was to find out and ascertain different clinical presentations of acne vulgaris in both sexes of various age groups and to find out the outcome of treatment with various topical modalities in various clinical types.
Methods: A total of 150 patients with acne vulgaris were studied with age group >10 years. Detailed history, thorough physical examination and relevant investigations were done. Patients were divided into 2 groups of 75 each and each group received different treatment and were followed up at 4th, 8th and 12th week.
Results: At the end of 12 weeks there was significant improvement in grade-II patients treated with cindamycin 1% gel.
Conclusions: The results of the study show that different grades of acne vulgaris respond with different regimens.
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References
Dawson AL, Dellavalle RP. Acne vulgaris. BMJ. 2013;346:f2634.
Leyden JJ. New understandings of the pathogenesis of acne. Journal of the American Academy of Dermatology 1995;32:S15-25.
Mahadevi P. Outcome of various topical modalities in acne vulgaris. 2012.
Lever L, Marks R. Current views on the aetiology, pathogenesis and treatment of acne vulgaris. Drugs. 1990;39:681-92.
Michalun MV, DiNardo JC. Skin care and cosmetic ingredients dictionary: Cengage Learning, 2014.
Tan X, Feldman SR, Chang J, Balkrishnan R. Topical drug delivery systems in dermatology: a review of patient adherence issues. Expert opinion on drug delivery 2012;9:1263-71.
Grant R. The history of acne. SAGE Publications, 1951.
Cordain L, Lindeberg S, Hurtad M, Hill K, Eaton Bbrand-Miller J. Acne vulgaris: A disease of Western Civilization. Arch Dermatol. 2002;138:1584-90.
Adityan B, Thappa DM. Profile of acne vulgaris-a hospital based study from South India. IJDVL. 2009;75(3):272-8.
Vaswani KN. Topical clindamycin hydrochloride 1% in acne vulgaris. Ind J Dermatol Venereol Leprol. 1990;56:377-80.
Lookingbill DP, Chalker DF, Lidholm, Katz HI, Kempers SE, Huerter CJ, et al. Treatment of acne with a combination of clindamycin/ benzoyl peroxide gel compared with clindamycin gel, benzyl peroxide gel and vehicle gel: Combined results of two double blind investigations. J Am Acad Dermatol. 1997;37:590-5.