Correlation between clinical, histopathological and direct immunoflourescence findings in cases of cicatricial alopecias

L. SornaKumar; C. Shanmuga Sekar; S. Vignesh

doi:10.18203/issn.2455-4529.IntJResDermatol20164041

Authors

L. SornaKumar Department of Dermatology, PSG hospitals, Coimbatore, India
C. Shanmuga Sekar Department of Dermatology, PSG hospitals, Coimbatore, India or PSG Hospitals Coimbatore
S. Vignesh Department of Dermatology, PSG hospitals, Coimbatore, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20164041

Keywords:

Cicatricial alopecias, Histopathological examination, Immunofluorescence

Abstract

Background: Cicatricial (scarring) alopecias form a group of disorders in which permanent hair loss results from replacement of follicles by fibrosis or hyalinized collagen. The aim was to find the correlation between clinical, histopathological and direct immunofluorescence findings in cicatricial alopecias.

Methods: A total of 20 cases were included in our study. Two 4mm punch biopsies were taken for haematoxylin and eosin (H & E) and DIF respectively. Vertical and horizontal section were cut and stained with haematoxylin and eosin.

Results: After histopathological examination 8 (40%) were confirmed as LPP, 6 (30%) as DLE, 2 (10%) as folliculitis decalvans and 1 (5%) each of acne keloidalis, trichotillomania, CTCL and morphea. Out of 8 confirmed cases of LPP 4 (50%) were positive for direct immunofluorescence and in 6 confirmed cases of DLE 4 (67%) were positive for immunofluorescence.

Conclusions: There was no statistical significance regarding the correlation between clinical, histopathological and immunofluorescence findings.

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Author Biographies

L. SornaKumar, Department of Dermatology, PSG hospitals, Coimbatore, India

Professor,Dept of Dermatology

C. Shanmuga Sekar, Department of Dermatology, PSG hospitals, Coimbatore, India or PSG Hospitals Coimbatore

Professor,Dept of Dermatology

S. Vignesh, Department of Dermatology, PSG hospitals, Coimbatore, India

Junior Resident,PSG Hospitals

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