Narrowband UVB versus psoralen – narrowband UVB in cases of chronic plaque type psoriasis: a matched pair study


  • C. Shanmuga Sekar Department of Dermatology, PSG hospitals, Coimbatore, India
  • L. Sorna Kumar Department of Dermatology, PSG hospitals, Coimbatore, India
  • Karthika Natarajan Department of Dermatology, PSG hospitals, Coimbatore, India
  • C. R. Srinivas Department of Dermatology, PSG hospitals, Coimbatore, India



Psoriasis, Narrowband UVB, Psoralen


Background: Psoriasis is a chronic inflammatory disease and various therapeutic options are available to treat the condition. The aim was to compare the efficacy of psoralen narrowband UV light (P-NBUVB) to conventional narrowband UVB light (NBUVB) in the treatment of psoriasis.

Methods: A total of 17 cases were included in our study. NBUVB was given on one half of the body and P-NBUVB was given on the other half and the response in two characteristic lesions was compared.

Results: The total lesional severity scale (TLSS) score of fourteen completed patients at the end of five sittings was 132 (mean- 9.42) for NBUVB and 127 (mean- 9.07) for P-NBUVB. The difference was not statistically significant. At the end of ten treatments the mean value was 5.76 for NBUVB and 4.92 for P-NBUVB.  There was statistical significance at this point. However by the end of our study, after fifteen treatments the mean value for NBUVB and P-NBUVB were 3.0 and 2.76 respectively which were statistically not significant.

Conclusions: We conclude that P-NBUVB was as effective as NBUVB in clearing psoriasis and further studies with larger study population is required to prove the efficacy of this treatment modality. 


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Original Research Articles