Nail: a window to systemic disease
Keywords:Plummer-Vinson syndrome, Esophageal webs, Dysphagia, Koilonychia
Plummer-Vinson syndrome is a rare clinical entity characterized by the triad of iron deficiency anemia, esophageal webs and dysphagia. The condition may manifest with the features like chelitis, glossitis, atropy of papilla over tongue, koilonychia indicating the underlying iron deficiency anemia and vitamin deficiency. We report a case of Plummer-Vinson syndrome presenting with koilonychia and chelitis. Clinical, laboratory and endoscopic evaluation of the patient revealed diagnosis of Plummer-Vinson syndrome. Patient was advised iron supplementation which significantly improved patient’s hemoglobin levels and with that the associated symptoms.
Hasan S, Khan NI, Siddiqui A. Plummer Vinson Syndrome-Apremalignant condition-an overviewof literature. J Med Dental Sci. 2013;1(1):28–30.
Bakshi SS. Plummer vinson syndrome—is it common in males? Arquivos de Gastroenterologia. 2015;52(3):250-2.
Plummer S. Diffuse dilatation of the esophagus without anatomic stenosis (cardiospasm): a report of 91 cases; J Am Med Assoc. 1912;58:2013-5.
Swain SK, Panigrahy R, Sahu MC. Plummer Vinson syndrome in amale and his chromosomal study—a case report. Egyptian J Med Human Genetics. 2015;16(3):283–6.
Novacel G. Plummer-Vinson syndrome. Orphanet J Rare Dis; 2006; 1:36.
Atmadzitis K, Papaziogas B, Pavlidis T. Plummer-Vinson syndrome; Dis Esophagus 2003;16(2):154-7.
Fawcett RS, Linford S, Stulberg DL. Nail abnormalities: clues to systemic disease. Am Fam Physician. 2004;69:1417–24.
Kumar G, Vaidyanathan L, Stead LG. Images in emergency medicine. Koilonychia, or spoon‐shaped nails, is generally associated with iron‐deficiency anemia. Ann Emerg Med. 2007;49:243-50.