Quality of life in psoriasis: a clinical study
Keywords:Psoriasis, Quality of Life, DLQI, Uttarakhand
Background: Psoriasis is a common inflammatory dermatosis with a chronic course that can have a significant detrimental effect on the quality of life (QoL) of those suffering from it. We conducted this study to evaluate the effect of psoriasis on QoL and to assess the impact of demographic factors and disease severity on QoL.
Methods: Ninety patients attending the Dermatology OPD at Himalayan Institute of Medical Sciences were included in the study. Their demographic details and history were recorded, followed by a physical examination including assessment of disease severity. DLQI was used to measure QoL. T-test and ANOVA were used to study the effect of demographic factors and disease severity on QoL. P<0.05 was considered statistically significant.
Results: Out of 90 patients, 61(67.78%) were males and 29 (32.22%) were females. The mean DLQI score was 15.00±4.93. QoL was impacted by age, sex, marital status and disease severity, whereas place of residence and educational status had no correlation with DLQI scores.
Conclusions: There is a marked negative impact on QoL of psoriasis sufferers; hence it becomes important to take the psycho-social aspect of the disease into consideration during treatment.
de Korte J, Sprangers MA, Mombers FM, Bos JD. Quality of life in patients with psoriasis: a systematic literature review. J Investig Dermatol Symposium Proc. 2004;9(2):140–7.
Gul A. Experience of anxiety and depression among psoriasis patients. Asian J Soc Sci Humanit. 2012;1(4):158–64.
Weiss SC, Kimball AB, Liewehr DJ, Blauvelt A, Turner ML, Emanuel EJ. Quantifying the harmful effect of psoriasis on health-related quality of life. J Am Acad Dermatol. 2002;47(4):512–8.
Dubertret L, Mrowietz U, Ranki A, van de Kerkhof PC, Chimenti S, Lotti T, et al. EUROPSO Patient Survey Group. European patient perspectives on the impact of psoriasis: the EUROPSO patient membership survey. Br J Dermatol. 2006;155(4):729-36.
Palijan TZ, Kovacevic D, Koic E, Ruzic K, Dervinja F. The impact of psoriasis on the quality of life and psychological characteristics of persons suffering from psoriasis. Coll Antropol. 2011;35(2):81-5.
Moons P, Budts W, De Geest S. Critique on the conceptualisation of quality of life: a review and evaluation of different conceptual approaches. Int J Nurs Stud. 2006;43(7):891-901.
Vettuparambil A, Asokan N, Narayanan B. Psoriasis can markedly impair the quality of life of patients irrespective of severity: Results of a hospital-based cross-sectional study. Muller J Med Sci Res. 2016;7(2):111–4.
Nijsten T. Dermatology life quality index:time to move forward. J Invest Dermatol. 2012;132(1):11-3.
Available at: http://mhrd.gov.in/sites/upload_files/ mhrd/files/statistics/ESG2016_0.pdf. Accessed on 3 January 2018.
Available at: http://censusindia.gov.in/2011-prov-results/paper2/data_files/India2/1.%20Data%20Highlight.pdf /Accessed 3 January 2017.
Yeung H, Takeshita J, Mehta NN, Kimmel SE, Ogdie A, Margolis DJ, et al. Psoriasis severity and the prevalence of major medical comorbidity: a population-based study. JAMA Dermatol. 2013;149(10):1173–9.
Lamb RC, Matcham F, Turner MA, Rayner L, Simpson A, Hotopf M, et al. Screening for anxiety and depression in people with psoriasis: a cross-sectional study in a tertiary referral setting. Br J Dermatol. 2017;176(4):1028-34.
Martins GA, Arruda L, Mugnaini ASB. Validation of life quality questionnaires for psoriasis patients. An Bras Dermatol. 2004;79(5):521-35
Barot PA, Brahmbhatt NY, Ninama HV, Kharadi DB, Malhotra SD. Quality of life in patients with psoriasis at a tertiary care teaching hospital –a cross sectional study. Natl J Med Res. 2015;5(2):93-7.
Mørk C, Wahl A, Moum T. The Norwegian version of the dermatology life quality index: A study of validity and reliability in psoriatics. Acta Derm Venereol. 2002;82(5):347-51.
Zachariae R, Zachariae C, Ibsen H, Mortensen JT, Wulf HC. Dermatology life quality index: data from Danish inpatients and outpatients. Acta Derm Venereol. 2000;80(4):272-6.
Yuwnate AH, Chandane RD, Sah RK. Impact of Acne and psoriasis on patient’s quality of life: A multicentre study from health-care centers in Wardha district. Natl J Physiol Pharm Pharmacol. 2017;7(5):522-6.
Eid AA, Elweshahi HM. Quality of life of Egyptian patients with psoriasis: a hospital based cross-sectional survey. Egypt J Dermatol Venerol. 2016;36(1):11-7.
Fatani MI, Habibullah TH, Alfif KA, Ibrahim AI, Althebyani B. Impact of Psoriasis on Quality of Life at Hera General Hospital in Makkah, Saudi Arabia. Clin Med Diagnostics. 2016;6(1):7-12.
Lin TY, See LC, Shen YM, Liang CY, Chang HN, Lin YK. Quality of life in patients with psoriasis in northern Taiwan. Chang Gung Med J. 2011;34(2):186–96
Tejada Cdos S, Mendoza-Sassi RA, Almeida HL Jr, Figueiredo PN, Tejada VF. Impact on the quality of life of dermatological patients in southern Brazil. An Bras Dermatol. 2011;86(6):1113-21.
Zachariae R, Zachariae H, Blomqvist K, Davidsson S, Molin L, Mørk C, et al. Quality of life in 6497 Nordic patients with psoriasis. Br J Dermatol. 2002;146(6):1006-16.
Sampogna F, Chren MM, Melchi CF, Pasquini P, Tabolli S, Abeni D. Age, gender, quality of life and psychological distress in patients hospitalized with psoriasis. Br J Dermatol. 2006;154(2):325–31.
McKenna KE, Stern RS. The impact of psoriasis on the quality of life of patients from the 16-center PUVA follow-up cohort. J Am Acad Dermatol. 1997;36(3):388-94.
Mabuchı T, Yamaoka H, Kojıma T, Ikoma N, Akasaka E, Ozawa A. Psoriasis Affects Patient’s Quality of Life More Seriously in Female than in Male in Japan. Tokai J Exp Clin Med. 2012;37(3):84–8.
Talamonti M, Galluzzo M, Servoli S, Chimenti S. Quality of Life Evaluation in Psoriasis Patients Starting a Biological Treatment: The Importance of a More Comprehensive Assessment of Disease Burden. EMJ Dermatol. 2015;3(1):87-91.
Valenzuela F, Silva P, Valdés MP, Papp K. Epidemiology and quality of life of patients with psoriasis in Chile. Actas Dermosifiliogr. 2011;102(10):810-6.
Goyal S, Pisharody RR, Nath S. Psychiatricmorbidity in psoriasis: A case-control study. J Mar Med Soc. 2017;19(1):18-23.
Pakran J, Riyaz N, Nandakumar G. Determinants of quality of life in psoriasis patients: A cluster analysis of 50 patients. Indian J Dermatol. 2011;56(6):689-93.
Silva MF, Fortes MR, Miot LD, Marques SA. Psoriasis: correlation between severity index (PASI) and quality of life index (DLQI) in patients assessed before and after systemic treatment. An Bras Dermatol. 2013;88(5):760-3.