Evaluation of platelet-rich plasma on infraorbital dark circles by using the FACE-Q scales


  • Kadri Ozer Plastic, Reconstructive and Aesthetic Surgery Clinic, Aydin State Hospital, Aydin, Istanbul, Turkey
  • Ozlem Colak Plastic, Reconstructive and Aesthetic Surgery Clinic, Istanbul Okmeydani Training and Research Hospital, Istanbul, Turkey




Dark circle, Hyperpigmentation, Infraorbital, Platelet-rich plasma


Background: Infraorbital dark circles, also referred to as idiopathic cutaneous hyperchromia of the orbital region, periorbital melanosis, periorbital hyperpigmentation or infraorbital pigmentation, is a common condition frequently observed in dark-skinned patients, but has little data in scientific literature. We aimed to discuss our results of PRP procedure in the treatment of infraorbital dark circles using objective scales based on patient satisfaction and the quality of life.

Methods: Between 2016 and 2017, 9 patients complaining of infraorbital darkness were included who underwent 3 sessions of platelet-rich plasma injection. The outcome was determined by the difference in pre- and post- procedure FACE-Q modules which were designed as patient-reported outcome instrument to evaluate the unique outcomes of patients undergoing facial cosmetic procedures. Surveys conducted were modules of satisfaction with facial appearance, satisfaction with skin, psychological function, social function, aging appearance appraisal and satisfaction with outcome.

Results: All patients were followed up a minimum of 9 months. No major complications were recorded. Only transient ecchymosis and edema were seen in all patients who were improved during follow-up. The patient-reported FACE-Q satisfaction and FACE-Q quality of life pre- and post- procedure results showed statistically significant improvement (<0.05). Overall satisfaction with outcome was 83.33±16.25 (range 63–100).

Conclusions: PRP as a potent source of growth factors, can be seen as a safe, biocompatible, autologous and appropriate treatment modality for the dark eye circles formed in lower eye regions which can increase the quality of patients’ lives in terms of social and psychological function.


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Original Research Articles