Neonatal pemphigus vulgaris

Authors

  • Santosh Kumar Singh Department of Dermatology, B.R.D. Medical College, Gorakhpur, Uttar Pradesh
  • Aayushi Mohan Department of Dermatology, B.R.D. Medical College, Gorakhpur, Uttar Pradesh
  • Anil Kumar Gupta Department of Dermatology, B.R.D. Medical College, Gorakhpur, Uttar Pradesh
  • Amit Kumar Pandey Department of Dermatology, B.R.D. Medical College, Gorakhpur, Uttar Pradesh

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20183173

Keywords:

Neonatal pemphigus, Desmoglein, Acantholysis, Self limiting

Abstract

Neonatal pemphigus is a transitory autoimmune blistering disorder caused by transplacental passage of maternal Auto antibodies to desmoglein to neonate through an affected mother. The association of maternal pemphigus vulgaris with neonate disease had been rarely reported. Herein, we report a case of neonatal pemphigus vulagris born to mother who conceived during active phase of disease. 

Metrics

Metrics Loading ...

References

Ian AG. Maternal Medicine: Medical Problems in Pregnancy, Dermatological disease in pregnancy, 1st ed. UK: Elsevier Health Sciences. 2007.

Wasserstrum N, Laros RK. Transplacental transmission of pemphigus. JAMA. 1983;249:1480–2.

Payne AS, Stanley JR. Fitzpatrick Dermatology in General Medicine. 8th edition. Chapter 54. 2012: 589.

Hilario-Vargas J, Vitorio IB, Stamey C, Culton DA, Prisayanh P, Rivitti EA, et al. Analysis of Anti-desmoglein 1 Autoantibodies in 68 Healthy Mother/Neonate Pairs from a Highly Endemic Region of Fogo Selvagem in Brazil. J Clin Exp Dermatol Res. 2014;5:209.

Shahir AK, Briggs N, Katsoulis J, Levidiotis V. An observational outcomes study from 1966-2008, examining pregnancy and neonatal outcomes from dialysed women using data from the ANZDATA Registry. Nephrology (Carlton). 2013;18:276–84.

Meurer M. Pemphigus diseases in children and adolescents. Hautarzt. 2009;60:208–16.

Lehman JS, Mueller KK, Schraith DF. Do safe and effective treatment options exist for patients with active Pemphigus vulgaris who plan conception and pregnancy? Arch Dermatol. 2008;144:783–5.

Daniel Y, Shenhav M, Botchan AM, Peyser R, Lessing JB. Pregnancy associated with pemphigus. Br J Obstet Gynecol. 1995;102:667–9.

Darling MR, Daley T. Blistering mucocutaneous diseases of the oral mucosa-a review: Part 2. Pemphigus vulgaris. J Can Dent Assoc. 2006;72:63-6.

Hertl M, Eming R, Veldman C. T cell control in autoimmune bullous skin disorders. J Clin Invest. 2006;116:1159–66.

Chowdhury MM, Natarajan S. Neonatal pemphigus vulgaris associated with mild oral pemphigus vulgaris in the mother during pregnancy. Br J Dermatol. 1998;139:500–3.

Gushi M, Yamamoto Y, Mine Y, Awazawa R, Nonaka K, Taira K, et al. Neonatal pemphigus vulgaris. J Dermatol. 2008;35:529-35.

Amer YB, Al Ajroush W. Pemphigus vulgaris in a neonate. Ann Saudi Med. 2007;27:453-5.

Panko J, Florell SR, Hadley J, Zone J, Leiferman K, Vanderhooft S. Neonatal pemphigus in an infant born to a mother with serologic evidence of both pemphigus vulgaris and gestational pemphigoid. J Am Acad Dermatol. 2009;60:1057-62.

Downloads

Published

2018-07-24