DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20180136

A clinico-epidemiological study on cutaneous leishmaniasis in Erbil, Iraq (2015-2017)

Zakarea Abdullah Yaseen Al-Khayat, Nabaz Fisal Shakir Agha, Kawthar Ibrahim Fatah Alharmni, Yousef Jafar Khudhur

Abstract


Background: The objective of the study was to determine the incidence of cutaneous leishmaniasis (CL) in Makhmur District (Erbil Province).

Methods: A cross-sectional, observational, descriptive study was performed in the outpatient clinic of Makhmur General Health Center. All the patients who presented at the dermatology clinic during the period from January 2015 to January 2017 were included in the study. The provisional diagnosis was dependent mainly on clinical examination in addition to Giemsa stain.

Results: A total of 1264 cutaneous leishmaniasis cases were diagnosed during the study period with males representing 54.6% of the cases. The study participants ranged from 10 months to 61 years. Age group <15 years were 53.5%. Clinically, 49.3% of patients had one lesion, 51.5% of patients had wet type. Most lesions were found on both limbs (48.8%). The highest number of cases was recorded during February (29.1%) and November (21.8%), while the lowest rate of cases was recorded in July (0.2%). According to stain results, 70.6% of the cases were positive to giemsa stain.

Conclusions: CL is endemic in Makhmur district. Males were infected in higher percent than females and this may be due to cultural, occupational and social factors.


Keywords


Epidemiology, Cutaneous leishmaniasis, Makhmur, Children, Endemic

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References


Rahi AA. Cutaneous Leishmaniasis in Iraq: A clinicoepidemiological descriptive study. Sch J App. Med Sci. 2013;1(6):1021-5.

Tabibian E, Shokouh SJH, Dehgolan SR, Moghaddam AD, Tootoonchian M, Noorifard M. Recent epidemiological profile of cutaneous leishmaniasis in Iranian military personnel. J Arch Mil Med. 2014;2(1):e14473.

Mollalo A, Alimohammadi A, Shahrisvand M, Shirzadi MR, Malek MR. Spatial and statistical analyses of the relations between vegetation cover and incidence of cutaneous leishmaniasis in an endemic province, northeast of Iran. Asian Pac J Trop Dis. 2014;4(3):176-80.

Amro A, Gashout A, Al-Dwibe H, Zahangir Alam M, Annajar B, Hamarsheh O, et al. First molecular epidemiological study of cutaneous leishmaniasis in Libya. PLoS Negl Trop Dis. 2012;6(6):e1700.

Bari Au, Rahman Sb. Correlation of clinical, histopathological, and microbiological findings in 60 cases of cutaneous leishmaniasis. Indian J Dermatol Venereol Leprol. 2006;72:28-32.

Al Samarai AM, AlObaidi HS. Cutaneous leishmaniasis in Iraq. J Infect Developing Countries. 2009;3(2):123-9.

Gandacu D, Glazer Y, Anis E, Karakis I, Warshavsky B, Slater P, et al. Resurgence of cutaneous leishmaniasis in Israel, 2001-2012. Emerg Infect Dis. 2014;20(10):1605–11.

Naqishbandi A. Demographic changes among inhabitant of Erbil districts. MSc thesis, Salahaddin University College of Educatin (2016).

Bensoussan E, Nasereddin A, Jonas F, Schnur, Jaffe C. Comparison of PCR Assays for diagnosis of cutaneous leishmaniasis. J Cli Microbiol. 2006;44(4):1435–9.

Yaghoobi-Ershadi MR. Epidemiological study in a new focus of cutaneous leishmaniasis in the Islamic Republic of Iran. East Mediterr Health J. 2003;9(4):816-26.

Fazaeli A, Fouladi B, Sharifi I. Emergence of cutaneous leishmaniasis in a border area at south-east of Iran: an epidemiological survey. J Vector Borne Dis. 2009;46(1):36-42.

Al-Obaidi MJ, Abd Al-Hussein MY, Al-Saqur IM. Survey Study on the Prevalence of Cutaneous Leishmaniasis in Iraq. Iraqi J Sci. 2016;57(3):2181-7.

Akcali C, Culha G, Inaloz HS, Savaş N, Önlen Y, Savaş L, et al. Cutaneous leishmaniasis in Hatay. J Turk Acad Dermatol. 2007;1(1):1-5.

Al-Mafraji KH, Al-Rubaey MG, Alkaisy KK. Clinco-Epidemiological Study of Cutaneous Leishmaniasis in Al-Yarmouk Teaching Hospital. Iraqi J Comm Med. 2008;21(3):194-7.

Sbehat W. Epidemiology of Cutaneous Leishmaniasis in the Northern West Bank, Palestine. Master Thesis in Public Health, Faculty of Graduate Studies,An- Najah National University, Nablus, Palestine. 2012.

Ahmadi NA, Modiri M, Mamdohi S. First survey of cutaneous leishmaniasis in Borujerd county, western Islamic Republic of Iran. East Mediterr Health J. 2013;19(10):847-53.

Ullah S, Jan AH, Wazir SH, Ali N. Prevalence of cutaneous leishmaniasis in Lower Dir District (NWFP), Pakistan. J Pakistan Assoc Dermatol. 2009;19(4):212–5.

Ok UZ, Balcioglu IC, Taylan Ozkan A, Ozensoy S, Ozbel Y. Leish¬maniasis in Turkey. Acta Trop. 2002;84(1):43–8.

da Silva Santos C, Brodskyn CI. The Role of CD4 and CD8 T Cells in Human Cutaneous Leishmaniasis. Front Public Health. 2014;2:165.

Ramírez JR, Agudelo S, Muskus C. Diagnosis of cutaneous leishmaniasis in Colombia: the sampling site within lesions influences the sensitivity of parasitologic diagnosis. J Clin Microbiol. 2000;38(10):3768-73.

El-Deen LD, Abul-Hab J, Abdulah SA. Clinico-epidemiological Study of Cutaneous Leishmaniasis in a Sample of Iraqi Armed Forces. Iraqi J Comm Med. 2006;19(2):89-103.

Bañuls AL, Bastien P, Pomares C, Arevalo J, Fisa R, Hide M. Clinical pleiomorphism in human leishmaniases, with special mention of asymptomatic infection. Clin Microbiol Infect. 2011;17(10):1451-61.

Kamali-Sarvestani E, Rasouli M, Mortazavi H, Gharesi-Fard B. Cytokine gene polymorphisms and susceptibility to cutaneous leishmaniasis in Iranian patients. Cytokine. 2006;35(3-4):159-65.

Mohammed WD. Toward an approach for cutaneous leishmania treatment. Our Dermatol Online. 2013;4(1):46-54.

Hepburn NC. Cutaneous leishmaniasis: an overview. J Postgrad Med. 2003;49:50-4.