Combination of platelet rich plasma and microneedling in the management of atrophic acne scars
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20173691Keywords:
Platelet rich plasma, Dermaroller, Atrophic acne scarsAbstract
Background: Acne scars have a lot of psychosocial implications, they are difficult to treat and can cause depression in the affected patient. The objective of the study was to assess the efficacy of combination of platelet rich plasma (PRP) injections and microneedling in the management of acne scars.
Methods: Thirty-five patients with atrophic acne scars were enrolled and graded using Goodman and Baron qualitative grading. Platelet rich plasma injection and microneedling were done at 2-week interval alternatively for a total of 6 sessions of each. Acne scars were graded before and 6 months after starting the treatment. Patients own evaluation of improvement was also recorded.
Results: A total of 12 patients had grade 4 acne scars, 8 (66.6%) improved to grade 2 and 4 (33.3%) improved to grade 3 scars. Out of 15 grade 3 scars, 8(53.3%) improved to grade 1, 7 (46.6%) improved to grade 2. 8 (100%) grade 2 patients improved to grade 1. All patients were highly satisfied with the results.
Conclusions: This combination has shown good results in all grades of acne scars.
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References
Layton AM. Psychosocial aspects of acne vulgaris. J Cutan Med Surg. 1998;2(3):19-23.
Fabbrocini G, Annunziata MC, D′Arco V, De Vita V, Lodi G, Mauriello MC, et al. Acne scars: Pathogenesis, classification and treatment. Dermatol Res Pract. 2010;2010:893080.
Jacob CI, Dover JS, KAminer MS. Acne scarring: A classification system and review of treatment options. J Am Acad Dermatol. 2001;45:109-17.
Salvin JW. Trichloroacetic acid peels. Aesthet Surg J. 2004;24:469-70.
Orentreich DS, Orentreich N. Subcutaneous incisionless (subcision) surgery for the correction of depressed scars and wrinkles. Dermatol Surg. 1995;21:543-9.
Alkhawam L, Alam M. Dermabrasion and microdermabrasion. Facial Plast Surg. 2009;25:301-10.
Hirsch RJ, Cohen JL. Soft tissue augmentation. Cutis. 2006;78:165-72.
Alexiades-Armenakas MR, Dover JS, Arndt KA. The spectrum of laser skin resurfacing: Nonablative, fractional, and ablative laser resurfacing. J Am Acad Dermatol. 2008;58:719-37.
Marx RE, Garg AK. Dental and Craniofacial Applications of Platelet-Rich Plasma. Chicago: Quintessence Publishing; 2005.
Bhanot S, Alex JC. Current applications of platelet gels in facial plastic surgery. Facial Plast Surg. 2002;18:27-33.
Goodman GJ, Baron JA. Postacne scarring: A qualitative global scarring grading system. Dermatol Surg. 2006;32:1458-66.
Aust MC, Reimers K, Repenning C, Stahl F, Jahn S, Guggenheim M, et al. Percutaneous collagen induction: Minimally invasive skin rejuvenation without risk of hyperpigmentation-fact or fiction. Plast Reconstr Surg. 2008;122:1553-63.
Majid I. Microneedling theraphy in atrophic facial scars: An objective assessment. J Cutan Aesthet Surg. 2009;2:26-30.
Fabbrocini G, De Vita V, Pastore F, Panariello L, Fardella N, Sepulveres R, et al. Combined use of skin needling and platelet-rich plasma in acne scarring treatment. Cosmet Dermatol. 2011;24:177-83.
Jaffe L. Control of development by steady ionic currents. Fed Proc. 1981;40:125-32.
Cohen KI, Diegelmann RF, Lindbland WJ. Wound healing; biochemical and clinical aspects. Philadelphia: WB Saunders Co; 1992.
Bernstein LJ, Kauvar AN, Grossman MC, Geronemus RG. The short- and long-term side effects of carbon dioxide laser resurfacing. Dermatol Surg. 1997;23:519-25.
Roy D. Ablative facial resurfacing. Dermatol Clin. 2005;23:549-59.
Ross EV, Naseef GS, McKinlay JR, Barnette DJ, Skrobal M, Grevelink J, et al. Comparision of carbon dioxide laser, erbium: YAG laser, dermabrasion, and dermatome: A study of thermal damage, wound contraction, and wound healing in a live pig model. Implications for skin resurfacing. J Am Acad Dermatol. 2000;42:92-105.
