Efficacy of skin care regime in improving biophysical parameters of skin: a split face clinical study

Machavolu Soubhagya Lakshmi Madhavi; Adarsh Kulkarni; Aditi Joshi; Aditi Kulkarni; Ankita Pawar; Neha Mawatwal; Rutuja Desai; Saurabh Mathur; Supriya Punyani

doi:10.18203/issn.2455-4529.IntJResDermatol20263743

Authors

Machavolu Soubhagya Lakshmi Madhavi R and D, Hindustan Unilever Ltd., Mumbai, India
Adarsh Kulkarni R and D, Hindustan Unilever Ltd., Mumbai, India
Aditi Joshi R and D, Hindustan Unilever Ltd., Mumbai, India
Aditi Kulkarni R and D, Hindustan Unilever Ltd., Mumbai, India
Ankita Pawar R and D, Hindustan Unilever Ltd., Mumbai, India
Neha Mawatwal R and D, Hindustan Unilever Ltd., Mumbai, India
Rutuja Desai R and D, Hindustan Unilever Ltd., Mumbai, India
Saurabh Mathur R and D, Hindustan Unilever Ltd., Mumbai, India
Supriya Punyani R and D, Hindustan Unilever Ltd., Mumbai, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20263743

Keywords:

Niacinamide, Hexylresorcinol, Glow

Abstract

Background: Background: Healthy and glowing skin is an aspired skin benefit among consumers and is linked to well-groomed appearance and self-esteem. Face cleansing is the first line of grooming practice as a part of hygiene among consumers. While these facial cleansers help to keep skin clean, skin also needs additional care as it is exposed to environmental pollution or solar radiation or other aggressors like dry or cold weather that can damage or strip of skin’s moisture, making it dry, rough and dull impacting the overall skin health.

Methods: The present clinical study is a randomized, mono centric, split face trial conducted in 40 healthy Indian female volunteers in the age group of 20-45 years. The objective of the study was to evaluate the efficacy of a face cleanser vs regime (face cleanser + face moisturiser) formulated with glycerol, niacinamide, 12-hydroxystearic acid and hexylresorcinol in improving skin hydration, brightness, glow and reducing the severity of dark spots.

Results: Both regime and face cleanser demonstrated improvement in glow, hydration and reduction in dark spot intensity on 2 weeks of regular use. Regime is significantly superior in all the biophysical parameters of skin. Both cleanser and regime are well accepted among the subjects without any adverse events like redness, itching or irritation.

Conclusions: While both face cleanser and regime demonstrated improvement in skin biophysical parameters, regime was significantly superior and accepted by participants for sustained skin benefits. Hence, it is recommended to adopt regime-based skin care treatments for sustained skin benefits.

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