ANCA-negative small vessel vasculitis: a case report in a 41-year-old male

Valeria Contreras Oceguera; Maria de Lourdes Ochoa Campollo

doi:10.18203/issn.2455-4529.IntJResDermatol20253738

Authors

Valeria Contreras Oceguera General Medicine, Private Practice, Guadalajara, Jalisco, Mexico
Maria de Lourdes Ochoa Campollo Department of Dermatology, Hospital Civil de Guadalajara, Jalisco, Mexico

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20253738

Keywords:

Small vessel vasculitis, Cutaneous vasculitis, Prednisone therapy

Abstract

Non-leukocytoclastic small vessel vasculitis is an uncommon inflammatory disorder characterized by vascular wall damage without evidence of leukocytoclasia. We present the case of a 41-year-old male with ANCA-negative small vessel vasculitis limited to the skin. The patient developed pruritic violaceous macules on the lower limbs and showed histopathologic findings of small-vessel vasculitis with neutrophilic infiltrate. Treatment with systemic corticosteroids resulted in favorable clinical evolution without recurrence. This case highlights the importance of comprehensive clinical assessment and individualized management in cutaneous vasculitis, emphasizing clinical judgment over immunological markers.

Metrics

Metrics Loading ...

References

Cassisa A, Cima L. Cutaneous vasculitis: insights into pathogenesis and histopathological features. Pathologica. 2024;116(2):119.

Hoffman GS, Calabrese LH. Vasculitis: Determinants of disease patterns. Nat Rev Rheumatol. 2014;10(8):454-62. DOI: https://doi.org/10.1038/nrrheum.2014.89

Jennette JC, Falk RJ, Bacon PA. 2012 Revised International Chapel Hill consensus conference nomenclature of vasculitides. Arthritis Rheum. 2013;65(1):1-11. DOI: https://doi.org/10.1002/art.37715

Potentas-Policewicz M, Fijolek J. Granulomatosis with polyangiitis: clinical characteristics and updates in diagnosis. Front Med (Lausanne). 2024;11:1369233. DOI: https://doi.org/10.3389/fmed.2024.1369233

Cassisa A, Cima L. Cutaneous vasculitis: insights into pathogenesis and histopathological features. Pathologica. 2024;116(2):119. DOI: https://doi.org/10.32074/1591-951X-985

Shavit E, Alavi A, Sibbald RG. Vasculitis—What Do We Have to Know? A Review of Literature. Int J Low Extrem Wounds. 2018;17(4):218-26. DOI: https://doi.org/10.1177/1534734618804982

Shahin MA, Khan MM, Shrestha S, Abdal SJ, Islam MA, Choudhury MR. Diagnosing of Small Vessel Vasculitis Might be a Challenge – A Rare Case Report. Bangladesh Med J. 2020;49(2):41-3. DOI: https://doi.org/10.3329/bmj.v49i2.55819

Naranjo-Velasco V, Pastor-Mena M, Rubio-Marín P, Anglada-Pintado JC. Síndrome constitucional y anemia como debut de vasculitis en un adulto mayor. Reporte de caso. Case Reports. 2021;7(2):68-76. DOI: https://doi.org/10.15446/cr.v7n2.89388

Pulido-Pérez A, Avilés-Izquierdo JA, Suárez-Fernández R. Vasculitis cutáneas. Actas Dermosifiliogr. 2012;103(3):179-91. DOI: https://doi.org/10.1016/j.ad.2011.06.001

Carmen M, Bravo P, Eugenia M, et al. Vasculitis de pequeños vasos: Análisis clínico, epidemiológico y terapéutico en 82 pacientes. Reumatología al Día. 2023;17(2):56. DOI: https://doi.org/10.62484/rad.v17i2.6662