Benign adnexal neoplasms of the skin: a 6-year histopathological review
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20252544Keywords:
Neoplasms, Adnexal and skin appendage, Skin, TumoursAbstract
Background: Tumours of the cutaneous appendages of the skin are a class of benign and malignant dermatological neoplasms, which present special morphological differentiation such as glandular, pilar or sebaceous.
Methods: A descriptive, observational, retrospective, and cross-sectional study focused on the histopathological diagnoses corresponding to benign neoplasms of the cutaneous appendages reported in the La Raza National Medical Center, México. For statistical analysis, descriptive statistics were used, with frequency distribution, percentage, mean, median.
Results: A total of 8,618 skin biopsy reports were analyzed. Of these, 222 were diagnoses of benign adnexal neoplasms. The prevalence was 2.57%. Of the total, 59.9% occurred in women and 40.1% in men. The median age was 56.9 years; in an age range from 61 to 70 years old. The most frequent anatomical location was the nose with 20.3%, followed by the lower extremities with 18.9%. Neoplasms with apocrine and eccrine differentiation were the most common, representing 55.9% of cases. Poroma was the most common subtype in our study, accounting for 19.37% of cases, followed by pilomatrixomas and trichodiscomas, both accounting for 15.77%.
Conclusions: Benign adnexal neoplasms of the skin have a prevalence of 2.57%. They occurred mostly in women aged 61 to 70 years. The most common adnexal tumor was poroma, and the most common location of appearance was the nose.
Metrics
References
Patterson J. Weedon's Skin Pathology. Fourth edition ed. Livingstone C, editor. London: Elsevier. 2016.
Goldblum J, Lamps L, McKenney J. Rosai and Ackerman’s Surgical Pathology. 11th ed. MA, editor. Cambridge: Elsevier. 2018.
Board WCoTE. Skin tumours. 5th ed. Cancer IAfRo, editor. Lyon (France): WHO Classification of Tumours Editorial Board. 2023.
Kikuchi K, Fukunaga S, Inoue H, Miyazaki Y, Ide F, Kusama K. Apocrine hidrocystoma of the lower lip: a case report and literature review. Head Neck Pathol. 2014;8(1):117-21. DOI: https://doi.org/10.1007/s12105-013-0451-2
Madhusudan DA, Vilas NV, Malladi N. Perianal eccrine syringofibroadenoma. Indian J Dermatol. 2017;62(5):548. DOI: https://doi.org/10.4103/ijd.IJD_566_16
Bürgesser M, Metrebián M, Kurpis M. Neoplasias anexiales de la piel. Revisión histopatológica de 8 años de experiencia. Revista Argentina de Dermatología. 2009;90(3):152-64.
Peralta-Pérez DC, Moreno-López LM, Mercadillo-Pérez P. Neoplasias cutáneas anexiales en población pediátrica: Estudio histopatológico de 20 años de experiencia. Dermatología Revista Mexicana. 2021;25(5):683-91.
Sánchez-Morales GE, Álvarez-Bautista FE, Aguilar-Romaro JM. Porocarcinoma ecrino. Tumor infrecuente de los anexos cutáneos. Gaceta Mexicana de Oncología. 2020;19(1):24-7. DOI: https://doi.org/10.24875/j.gamo.19000302
Fernández Díez JR. Neoplasias malignas de anexos cutáneos. Experiencia con 247 casos. Patología Revista latinoamericana. 2011;49(1):11-24.
Lee JS, Park H, Yoon HS. Eccrine Syringofibroadenoma Associated with Bowen's Disease: A Case Report and Review of the Literature. Ann Dermatol. 2020;32(1):57-63. DOI: https://doi.org/10.5021/ad.2020.32.1.57
González L, Di Martino B, Rodríguez M, Knopfelmacher O, Bolla L, Recalde J. Estudio clínico y epidemiológico de los tumores anexiales en la cátedra de Dermatología de la Facultad de Ciencias Médicas de la Universidad Nacional de Asunción. Paraguay, 2002-2008. Folia Dermatológica Peruana. 2009;20(3):135-9.
Yaqoob N, Ahmad Z, Muzaffar S, Gill MS, Soomro IN, Hasan. Spectrum of Cutaneous Appendage Tumors at Aga Khan University Hospital. J Pak Med Associat. 2003;53(9):427-31.
Ireland A, Harvey N, Berry B, Wood B. Paediatric cutaneous adnexal tumours: a study of 559. Anatomical Pathol. 2017;49(1):50-4. DOI: https://doi.org/10.1016/j.pathol.2016.10.003
Cook S, Bajwa D, Hollestein LM, Husain A, Rajan N. A 5-year retrospective review of skin adnexal tumours received at a tertiary dermatopathology service: Implications for linked genetic diagnoses. Brit J Dermatol. 2022;186(1):167-73. DOI: https://doi.org/10.1111/bjd.20701
Samaila M. Adnexal skin tumors in Zaria, Nigeria. Ann Afr Med. 2008;7(1):6-10. DOI: https://doi.org/10.4103/1596-3519.55691
Kamyab-Hesari K BKANea. Clinicopathological Study of 1016 Consecutive Adnexal Skin Tumors. Acta Medica Iranica. 2013;51(1):879-85.
Muñoz Martínez R, Cortez Gómez RG. Iatrogenia pandémica: la exclusión y el rezago en la atención médica, no COVID, en la Ciudad de México. Ciênc Saúde Coletiva. 2022;27(11):4155-46. DOI: https://doi.org/10.1590/1413-812320222711.03332022en
Alsaad K, Obaidat N, Ghazarian D. Skin adnexal neoplasms-part 1: An approach to tumours of the pilosebaceous unit. J Clin Pathol. 2007;60(2):129-44. DOI: https://doi.org/10.1136/jcp.2006.040337
Downloads
Published
How to Cite
Issue
Section
