Cutaneous leishmaniasis: an enigma of rare clinical presentations
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20251048Keywords:
Cutaneous leishmaniasis, Atypical presentation, BiopsyAbstract
Leishmaniasis is a neglected tropical disease caused by leishmania parasite. It is divided into two groups: old world species like L. major, L. infantum, and L. tropica and new world species such as L. amazonensis, L. mexicana, L. panamensis, L. braziliensis, and L. guyanensis. In India, cutaneous leishmaniasis (CL) cases are mostly seen in Rajasthan, Delhi, Himachal Pradesh, Haryana, Jammu and Kashmir with few isolated reports from south India as well. J and K over the past few years has emerged as a hot spot of CL. Although majority of the cases show classical presentation, atypical presentations mimicking various dermatoses are witnessed. As a clinician, we need to have a high index of suspicion to confirm the diagnoses. Moreover, in an endemic area, it is imperative for the physician to be well acquainted that any atypical lesion, especially chronic form, should be investigated for CL.
Metrics
References
CDC. Epidemiology and risk factors. Available at: https://www.cdc.gov/parasites/leishmaniasis/epi.html. Accessed on 12 January 2025.
Alvar J, Vélez ID, Bern C, Mercé H, Philippe D, Jorge C, et al. Leishmaniasis worldwide and global estimates of its incidence. PLoS One. 2012;7(5):e35671. DOI: https://doi.org/10.1371/journal.pone.0035671
Kaul N, Gupta V, Bhardwaj S, Devraj D, Naina D. A new focus of cutaneous leishmaniasis in Jammu division of Jammu and Kashmir State, India. Indian J Dermatol Venereol Leprol. 2016;82(2):145-50. DOI: https://doi.org/10.4103/0378-6323.175930
Shagufta R, Wani M, Shah YF, Safia B, Atiya Y, Firdous AG. Clinical and epidemiological study of cutaneous leishmaniasis in two tertiary care hospitals of Jammu and Kashmir: An emerging disease in North India RatInternational J Infect Dis. 2021;103:138-45. DOI: https://doi.org/10.1016/j.ijid.2020.11.002
Masood Q, Majid I, Hassan I. Cutaneous Leishmaniasis in Kashmir: a new phenomenon. KMJ. 2009;3:395-7.
Aara N, Khandelwal K, Bumb RA. Clinco-epidemiologic study of cutaneous Leishmaniasis in Bikaner, Rajasthan, India. Am J Trop Med Hyg. 2013;89:111-5. DOI: https://doi.org/10.4269/ajtmh.12-0558
Thakur L, Singh KK, Shanker V, Negi A, Jain A, Matlashewski G, et al. Atypical leishmaniasis: a global perspective with emphasis on the Indian subcontinent. PLoS Negl Trop Dis. 2018;12:e0006659. DOI: https://doi.org/10.1371/journal.pntd.0006659
Siriwardana Y, Deepachandi B, Gunasekara C, Warnasooriya W, Karunaweera ND. Leishmania donovani induced cutaneous leishmaniasis: an insight into atypical clinical variants in Sri Lanka. J Trop Med. 2019;2019:4538597. DOI: https://doi.org/10.1155/2019/4538597
Pires CAA, Pereira NG, Moreira AG, Sena JMC, Costa CCC, Bastos TDS, et al. Cutaneous leishmaniasis mimicking cutaneous lymphoma. IDCases. 2019;17:e00580. DOI: https://doi.org/10.1016/j.idcr.2019.e00580
Alkhawajah AM, Larbi E, Al-Gindan Y, Abahussein A, Jain S. Treatment of cutaneous Leishmaniasis with antimony: Intramuscular versus intralesional administration. Ann Trop Med Parasitol. 1997;91(8):899-905. DOI: https://doi.org/10.1080/00034983.1997.11813217
Ines Z, Faten I, Rym K, Dalenda El E, Mourad M, Emna C, et al. Childhood and adult cutaneous Leishmaniasis in Tunisia. Int J Dermatol. 2010;49(7):790-93. DOI: https://doi.org/10.1111/j.1365-4632.2010.04467.x