Discoid lupus erythematosus leading to squamous cell carcinoma: a case report

Dadapeer H. J.; Anupama Y. G.; Sushma D. M.

doi:10.18203/issn.2455-4529.IntJResDermatol20173930

Authors

Dadapeer H. J. Department of Dermatology and STD, Shimoga Institute of Medical Sciences, Shimoga, Karnataka
Anupama Y. G. Department of Dermatology and STD, Shimoga Institute of Medical Sciences, Shimoga, Karnataka
Sushma D. M. Department of Dermatology and STD, Shimoga Institute of Medical Sciences, Shimoga, Karnataka

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20173930

Keywords:

Discoid lupus eryhtematosus, Squamous cell carcinoma, Carpet tack sign

Abstract

Discoid lupus erythematosus (DLE) is the most common chronic form of cutaneous lupus. It is characterised by persistent scaly, disk-like plaques on scalp, face and ears that may cause pigmentary changes, scarring and hair loss. Squamous cell carcinoma can rarely arise within a longstanding DLE plaque in the skin. It presents as an enlarging warty growth or ulcer. We report a case of squamous cell carcinoma which developed on lesion of discoid lupus erythematosus within a short period of time.

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Author Biographies

Dadapeer H. J., Department of Dermatology and STD, Shimoga Institute of Medical Sciences, Shimoga, Karnataka

Department of dermatolgy

Anupama Y. G., Department of Dermatology and STD, Shimoga Institute of Medical Sciences, Shimoga, Karnataka

Department of Dermatology

References

Winfield H, Jaworsky C. Connective tissue diseases. In :Elder DE, Elenitsas R, Johnson BL, Murphy GF, Xu X (eds). Lever’s histopathology of the skin, 10th ed. Philadelphia: Lippincott Williams and Wilkins; 2009: 279-310

Cassarino DS, Derienzo DP, Barr RJ. Cutaneous squamous cell carcinoma: A Comprehensive clinicopathologic classification. J Cutan Pathol. 2006;33:191-206.

Grover S, Murthy PS, Rajagopal R, Jalpota YP, Sudha KV. Discoid lupus erythematous leading to squamous cell carcinoma. Med J Armed Forces India. 2007;63:184-5.

Dhingra M, Bhalla M, Thami GP, Mittal P. Metastasizing squamous cell carcinoma arising from chronic discoid lupus erythematosus plaque of recent onset. Indian J Dermatol Venereol Leprol. 2011;77:626.

Bhat MR, Hulmani M, Dandakeri S, Kambil SM, Gatti R. Disseminated discoid lupus erthyematous leading to squamous cell carcinoma. Indian J Dermatol. 2012:57:158-61.

Tao J, Zhang X, Guo N. Squamous cell Carcinoma complicating discoid lupus erythematosus in Chinese patients: Review of the literature. 1964-2010. J Am Dermatol. 2012;66: 695-6.

Sherman RN, Lee CW, Flynn KJ. Cutaneous squamous cell carcinoma in black patients with chronic discoid lupus erythematosus. Int J Dermatol. 1993;32:677-9.

Gupta U, Barman KD, Saify K. Squamous cell carcinoma complicating an untreated chronic discoid lupus erythematosus (CDLE) lesion in a black female. J Dermatol. 2005;32:1010-3.