Skin disorders in patients with type 2 diabetes mellitus in Khartoum Dermatology and Venereology Teaching Hospital
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20242652Keywords:
KDVTH, DM, Diabetic dermopathy, Acanthosis nigricans, Xerosis, Tinea pedisAbstract
Background: Diabetes is a chronic, metabolic disease characterized by elevated levels of blood glucose, which leads over time to serious damage to the heart, blood vessels, eyes, kidneys and nerves. The most common is type 2 diabetes, usually in adults, which occurs when the body becomes resistant to insulin or doesn't make enough insulin. About 1 in 11 adults worldwide now have diabetes mellitus (DM), 90% of whom have type 2 DM (T2DM). One of the most common manifestations of diabetes are skin complications, such as dryness of the skin, bacterial and fungal infections. Objectives were to study the frequency and pattern of skin disorders in patients with T2DM at Khartoum dermatology and venereology teaching hospital (KDVTH) in Khartoum, Sudan during August 2016 to December 2016.
Methods: This was prospective, observation descriptive, cross-sectional hospital-based study used a quantities method. A total convenient sample technique enrolled 100 points during the study period.
Results: One hundred diabetic patients (64% male and 36% female) were included in the study. The age group varies between (25 and >70 years), the commonest cutaneous manifestations were xerosis which was found in 45 patients (45%), fungal infection found in 36 patients (36%). Serum HbA1c level was done for each case
Conclusions: The study concluded that the most prevalent cutaneous diseases among patients were xerosis fungal infection, eczema, bacterial infections, and scabies respectively. A significant relationship between duration of DM and level of HB A1C and the presence of cutaneous manifestations was observed.
References
Diabetes. 2023. Available at: https://www.who.int/ news-room/fact-sheets/detail/diabetes. Accessed on 15 June 2024.
Wang YR, Margolis D. The prevalence of diagnosed cutaneous manifestations during ambulatory diabetes visits in the United States, 1998-2002. Dermatology. 2006;212(3):229-34.
Federation ID. IDF diabetes atlas. Brussels: International Diabetes Federation, 6th edi. 2013.
Sanad EM, ElFangary MM, Sorour NE, ElNemisy NM. Skin manifestations in Egyptian diabetic patients: a case series study. Egypt J Dermatol Venereol. 2013;33(2):56-62.
Goyal A, Raina S, Kaushal SS, Mahajan V, Sharma NL. Pattern of cutaneous manifestations in diabetes mellitus. Indian J Dermatol. 2010;55(1):39-41.
Campos GM, Nunes S, Barreto T. Skin disorders in diabetes mellitus: an epidemiology and physiopathology review. Diabetol Metab Syndr. 2016;8(1):63.
Demirseren DD, Emre S, Akoglu G, Dilek A, Aysegul A, Ahmet M, et al. Relationship between skin diseases and extracutaneous complications of diabetes mellitus: clinical analysis of 750 patients. Am J Clin Dermatol. 2014;15(1):65-70.
Hattem SV, Bootsma AH, Thio HB. Skin manifestations of diabetes. Cleveland Clin J Med. 2008;75(11):772-87.
Ahmed K, Muhammad Z, Qayum I. Prevenance of cutaneous manifestations of diabetes mellitus. J Ayub Med Coll Abbottabad. 2009;21(2):77-8.
Almansour M, Abanemai N, Alhusayni S, Forat A, Ruba A, Ghaiath H. Perception of Attendees of Primary Healthcare Centers in Al-Majmaah City, Saudi Arabia About Skin Manifestations of Diabetes Mellitus. J Res Med Dental Sci. 2020;8(4):43-50.
Niaz F, Bashir F, Nadia S, Zaman S, Ijaz A. Cutaneous manifestations of diabetes mellitus type 2: prevalence and association with glycemic control. J Pak Assoc Dermatolog. 2016;26(1):4-11.
Bashier AH, Kordofani YM. Clinico-epidemiological study of cutaneous manifestations of diabetes mellitus in Sudanese patients. Sud J Dermatol. 2004;2(2):54-60.
Kalus AA, Chien AJ, Olerud JE. Diabetes mellitus and other endocrinal disorder. In: Fitzpatrick’s Dermatology in general medicine. 7th ed. New York: Mc Graw-Hill. 2008;1461-84.
Crook MA. Skin tags and atherogenic lipid profile. J Clin Pathol. 2000;53(11):873-4.