Role of skin circadian rhythm and the effect of day and night cream: a survey on Indian dermatologists’ and cosmetologists’ views and patient experiences
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20242302Keywords:
Skin circadian rhythm, Day cream, Night cream, Day and night creamAbstract
Background: The skin plays different functions during the day and night to adapt to the changing environments. Various specialized creams are available to meet these skincare needs. The present study was conducted to explore the perspective of Indian dermatologists and cosmetologists on skin’s circadian rhythm and assess the effectiveness of a particular day and night cream formulation.
Methods: A non-interventional, questionnaire-based study was conducted as part of a survey series on multiple dermatology products across India. Every month, a product-specific survey link was released to these registered doctors, and each doctor could take up to 10 surveys for a maximum of two products. A total of 379 healthcare professionals (HCPs) took the survey on the day and night cream and reported experiences of 2085 patients regarding the use of these products.
Results: The doctors believed that for majority of the patients (1997, 97%), required day and night cream to maintain their skin’s circadian rhythm. Most patients (1440, 70%) were compliant with day and night care cream regimens. Most patients (966, 47%) were highly satisfied with the use of day and night cream, with majority of the patients (1028, 49.4%) experiencing considerable reduction in dark spots and uneven skin tone. Most patients (971, 47%) felt that the application of day and night cream left their skin moisturized and rejuvenated.
Conclusions: The use of day and night cream improved skin condition and hydration, addressing circadian rhythm imbalance. Indian HCPs understand the impact of skin circadian rhythm imbalance and promote a comprehensive skincare regimen to patients.
Metrics
References
Plikus MV, Van Spyk EN, Pham K, Geyfman M, Kumar V, Takahashi JS, et al. The circadian clock in skin: implications for adult stem cells, tissue regeneration, cancer, aging, and immunity. J Biol Rhythms. 2015;30(3):163-82.
Duan J, Greenberg EN, Karri SS, Andersen B. The circadian clock and diseases of the skin. FEBS Lett. 2021;595(19):2413-36.
Matsui MS, Pelle E, Dong K, Pernodet N. Biological Rhythms in the Skin. Int J Mol Sci. 2016;17(6):801.
Santoro F, Teissedre S. A Novel Night Moisturizer Enhances Cutaneous Barrier Function in Dry Skin and Improves Dermatological Outcomes in Rosacea-prone Skin. J Clin Aesthet Dermatol. 2018;11(12):11-7.
Lyons AB, Moy L, Moy R, Tung R. Circadian Rhythm and the Skin: A Review of the Literature. J Clin Aesthetic Dermatol. 2019;12(9):42.
Rattanawiwatpong P, Wanitphakdeedecha R, Bumrungpert A, Maiprasert M. Anti-aging and brightening effects of a topical treatment containing vitamin C, vitamin E, and raspberry leaf cell culture extract: A split-face, randomized controlled trial. J Cosmet Dermatol. 2020;19(3):671-6.
Draelos ZD. Revisiting the Skin Health and Beauty Pyramid: A Clinically Based Guide to Selecting Topical Skincare Products. J Drugs Dermatol. 2021;20(6):695-9.
Rodan K, Fields K, Majewski G, Falla T. Skincare Bootcamp: The Evolving Role of Skincare. Plast Reconstr Surg Glob Open. 2016;4(12):e1152.
Messaraa C, Robertson N, Walsh M, Hurley S, Doyle L, Mansfield A, et al. Clinical evidences of benefits from an advanced skin care routine in comparison with a simple routine. J Cosmet Dermatol. 2020;19(8):1993-9.
Michalak M, Pierzak M, Kręcisz B, Suliga E. Bioactive Compounds for Skin Health: A Review. Nutrients. 2021;13(1):203.
Thiele JJ, Hsieh SN, Ekanayake-Mudiyanselage S. Vitamin E: critical review of its current use in cosmetic and clinical dermatology. Dermatol Surg. 2005;31(7 Pt 2):805-13.
Juncan AM, Moisă DG, Santini A, Morgovan C, Rus LL, Vonica-Țincu AL, et al. Advantages of Hyaluronic Acid and Its Combination with Other Bioactive Ingredients in Cosmeceuticals. Molecules. 2021;26(15):4429.
Escobar S, Valois A, Nielsen M, Closs B, Kerob D. Effectiveness of a formulation containing peptides and vitamin C in treating signs of facial ageing: three clinical studies. Int J Cosmet Sci. 2021;43(2):131-5.