Hair dye allergies: available alternatives

Sukanya Gurusamy; Celestin Geo Danny; Gayathri S.; Divyabharathi Sundarara

doi:10.18203/issn.2455-4529.IntJResDermatol20241729

Authors

Sukanya Gurusamy Department of Dermatology, Venereology and Leprosy, Sri Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
Celestin Geo Danny Department of Dermatology, Venereology and Leprosy, Sri Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
Gayathri S. Department of Dermatology, Venereology and Leprosy, Sri Balaji Medical College and Hospital, Chennai, Tamil Nadu, India
Divyabharathi Sundarara Department of Dermatology, Venereology and Leprosy, Sri Balaji Medical College and Hospital, Chennai, Tamil Nadu, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20241729

Keywords:

Paraphenylenediamine, Allergic contact dermatitis, Two-methoxymethyl-p-phenylenediamine, Hydroxyethyl-p-phenylenediamine, Sensitizing potential, Hair dye molecules, Cross elicitation response

Abstract

P-phenylenediamine (PPD) is a well-known sensitizer of skin which forms a major component in permanent hair dyes. Allergic contact dermatitis induced by PPD is a major concern for hairdye industry and the population using hair dyes. To reduce the burden of contact dermatitis due to PPD in hair dyes, various alternative hair dye molecules have been developed over the years which include two-methoxymethyl-p-phenylenediamine (ME-PPD) molecule and hydroxyethyl-p-phenylenediamine (HE PPD) molecule. These both molecules have shown reduced sensitization to skin and much lower skin permeability which makes them as safer alternatives to PPD hair dyes in the market.

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