Basaloid follicular hamartoma: an infrequent entity

Authors

  • Tarra Reshma Department of Dermatology, Maharajah Institute of Medical Sciences, Vizianagaram, Andhra Pradesh, India
  • K. V. T. Gopal Department of Dermatology, Maharajah Institute of Medical Sciences, Vizianagaram, Andhra Pradesh, India
  • P. V. Krishnam Raju Department of Dermatology, Maharajah Institute of Medical Sciences, Vizianagaram, Andhra Pradesh, India
  • B. Rekha Rani Department of Dermatology, Maharajah Institute of Medical Sciences, Vizianagaram, Andhra Pradesh, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20241725

Keywords:

Basaloid follicular hamartoma, Benign tumor, Basaloid cells

Abstract

Basaloid follicular hamartoma is a rare, benign, skin adnexal tumor. Several clinical patterns have been reported, but they all share the same histopathological features. BFH may be hereditary or nonhereditary and can be accompanied by systemic diseases. Microscopic examination of BFH shows branching cords and anastomosing strands of basaloid cells in a loose, fibrous stroma. The most important pathological differential diagnosis is infundibulocystic basal cell carcinoma. These two lesions must be differentiated carefully based on clinical presentation and histopathological picture, and even molecular studies may be needed. We report a case of 60 year old female who came with a complaint of asymptomatic dark colored raised lesion over right side of face since 2 years. On evaluation lab investigations were found to be normal and histopathological examination showed interanastomosing cords and nests of basaloid cells, few abortive hair papillae and prominent melanophages. Based on these changes patient was diagnosed with basalloid follicular hamartoma and was advised for surgical excision.

References

Brown AC, Crounse RG, Winkelmann RK. Generalized hair-follicle hamartoma, associated with alopecia, aminoacidura, and myasthenia gravis. Arch Dermatol. 1969;99:478-93.

El-Darouti MA, Marzouk SA, Abdel-Halim MR, Zidan AZ, Fawzy MM. Basaloid follicular hamartoma. Int J Dermatol. 2005;44:361-5.

Mills O, Thomas LB. Basaloid follicular hamartoma. Arch Pathol Lab Med. 2010;134:1215-9.

Mehregan AH, Baker S. Basaloid follicular hamartoma:three cases with localized and systematized unilateral lesions. J Cut Pathol. 1985;12: 55-65.

Patel AB, Harting MS, Smith-Zagone MJ, Hsu S. Familial basaloid follicular hamartoma: A report of one family. Dermatol Online J. 2008;14:14.

El-Darouti MA, Marzouk SA, Abdel-Halim MR, Zidan AZ, Fawzy MM. Basaloid follicular hamartoma. Int J Dermatol. 2005;44:361-5.

Nelson BR, Johnson TM. Basaloid follicular hamartoma: a histologic diagnosis with diverse clinical presentations. Arch Dermatol. 1993;3:129.

Brownstein MH. Basaloid follicular hamartoma: solitary and multiple types. J Am Acad Dermatol. 1992;14:27237-40.

Toyoda M, Kagoura M, Morohashi M. Solitary basaloid follicular hamartoma. J Dermatol. 1998;25: 434-7.

Segars K, Cooper H. Basaloid follicular hamartoma: a case report and a novel cosmetic treatment. J Clin Aesthet Dermatol. 2018;11:39-41.

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Published

2024-06-26

Issue

Section

Case Reports