A multicentric, prospective, observational study evaluating the use patterns of Sebium night peel for acne-prone skin and associated conditions
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20232537Keywords:
Acne, Acne-related sequelae, Chemical peeling agent, Study, Sebium night peelAbstract
Background: Acne is a common skin disorder that affects both adolescents and adults and is categorized as an inflammatory dermatosis. Persistent adult acne is prevalent in more than 80% of cases. Chemical peels are widely used in acne therapy due to their various benefits, including exfoliation, acne lesion reduction, complexion radiance improvement, and scar repair. The procedure, consisting of 2 to 8 sessions, is ideal for adult women with oily skin, acne breakouts, and concerns about photoaging and complexion radiance.
Methods: A cohort of Indian dermatologists were provided a questionnaire related to the quantum of weekly acne patients seen and their clinical expertise regarding the use of Sebium Night Peel containing 15% glycolic acid, the Fluidactiv™ patented complex & D-panthenol. These results were later analyzed using a standardised visual analogue scale.
Results: The study enrolled 826 patients, and complete responses were received from 73 dermatologists practicing clinical and aesthetic dermatology across major cities in India. The study revealed that 97% of dermatologists would recommend the Sebium Night Peel as a chemical peel for patients with acne and acne-related complications. The majority of dermatologists rated the peel's tolerability and safety as "good" across various evaluation criteria. Additionally, 97% of dermatologists reported no safety concerns associated with the Sebium Night Peel.
Conclusions: This study establishes the Sebium Night Peel as a preferred and effective chemical peel for managing acne-prone skin and associated conditions, as endorsed by dermatologists across India.
References
Bickers DR, Lim HW, Margolis D. The burden of skin diseases: 2004 a joint project of the American Academy of Dermatology Association and the Society for Investigative Dermatology. J Am Acad Dermatol. 2006;55(3):490-500.
Dayal S, Amrani A, Sahu P, Jain VK. Jessner’s solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-tomoderate acne vulgaris. J Cosmet Dermatol. 2017;16(1):43-51.
Al-Talib H, Al-Khateeb A, Hameed A, Murugaiah C. Efficacy and safety of superficial chemical peeling in treatment of active acne vulgaris. An Bras Dermatol. 2017;92(2):212-6.
Gollnick H. Current concepts of the pathogenesis of acne: implications for drug treatment. Drugs. 2003; 63(15):1579-96.
Kurokawa I, Oiso N, Kawada A. Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non-inflamed atrophic scars in acne vulgaris. J Dermatol. 2017;44(4):401-5.
Hosthota A, Bondade S, Basavaraja V. Impact of acne vulgaris on quality of life and self-esteem. Cutis. 2016;98(2):121-4
Castillo DE, Keri JE. Chemical peels in the treatment of acne: patient selection and perspectives. Clin Cosmet Invest Dermatol. 2018:365-72.
Singh-Behl D, Tung R. Chemical peels. In: Alam M, Tung R, Gladstone H, eds. Cosmetic Dermatology. USA: Saunders Elsevier; 2009.
Clark E, Scerri L. Superficial and medium-depth chemical peels. Clin Dermatol. 2008;26(2):209-18.
Tse Y. Choosing the correct peel for the appropriate patient. In: Tung R, Rubin M, eds. Procedures in Cosmetic Dermatology Series: Chemical Peels. 2nd ed. London: Elsevier Health Sciences; 2010:17-21.
Rendon MI, Berson DS, Cohen JL. Evidence and considerations in the application of chemical peels in skin disorders and esthetic resurfacing. J Clin Aesthet Dermatol. 2010;3(7):32-43.
Costa IM, Damasceno PS, Costa MC, Gomes KG. Review in peeling complications. J Cosmet Dermatol. 2017;16(3):319-26.
Kontochristopoulos G, Platsidaki E. Chemical peels in active acne and acne scars. Clin Dermatol. 2017;35(2):179-82.
Kessler E, Flanagan K, Chia C, Rogers C, Glaser DA. Comparison of alpha- and beta-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris. Dermatol Surg. 2008;34:45-50.
Taub AF. Procedural treatments for acne vulgaris. Dermatol Surg. 2007;33:1005-26.
Kim SW, Moon SE, Kim JA, Eun HC. Glycolic acid versus Jessner's solution: Which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. Dermatol Surg. 1999;25: 270-3.
Baumann L, Saghari S. Chemical Peels. In: Baumann L, editor. Cosmetic Dermatology. 2nd ed. New York: McGraw-Hill; 2002:48-60
Fabbrocini G, De Padova MP, Tosti A. Glycolic Acid. Color Atlas of Chemical Peels. Heidelberg: Springer; 2002.
Ebner F, Heller A, Rippke F, Tausch I. Topical use of dexpanthenol in skin disorders. Am J Clin Dermatol. 2002;3(6):427-33.
André P, Villain F. Free radical scavenging properties of mannitol and its role as a constituent of hyaluronic acid fillers: a literature review. Int J Cosmet Sci. 2017;39(4):355-60.