Cyclophosphamide and varicella zoster virus induced disseminated intravascular coagulopathy with fatal outcome


  • A. S. Salunke Department of Skin and V.D., B.J.G.M.C., Pune, Maharashtra
  • V. A. Belgaumkar Department of Skin and V.D., B.J.G.M.C., Pune, Maharashtra
  • R. B. Chavan Department of Skin and V.D., B.J.G.M.C., Pune, Maharashtra
  • S. S. Tharewal Department of Skin and V.D., B.J.G.M.C., Pune, Maharashtra



Pemphigus vulgaris, Varicella zoster virus, Disseminated intravascular coagulopathy, Cyclophosphamide


Varicella is usually a mild self-limiting disease, commonly occurring in paediatric population. However, in adults and in specific groups of patients, such as those who are immunosuppressed, varicella virus infections can be fulminant and life threatening. We are hereby reporting two cases of Pemphigus vulgaris on cyclophosphamide therapy, who succumbed due to disseminated intravascular coagulopathy (DIC) after varicella zoster virus infection. 


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