Recurrent vesicular palmoplantar dermatitis: a clinical study in children and adolescents

Mrudula S.; Thokchom Nandakishore; Linda Kongbam; Bhavya Valsalan; Nischith V.; Lalthlamuana Ralte

doi:10.18203/issn.2455-4529.IntJResDermatol20230454

Authors

Mrudula S. Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India
Thokchom Nandakishore Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India
Linda Kongbam Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India
Bhavya Valsalan Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India
Nischith V. Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India
Lalthlamuana Ralte Department of Dermatology, Venereology and Leprology, Regional Institute of Medical Sciences, Imphal, Manipur, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20230454

Keywords:

Dyshidrosis, Pompholyx, Children, Hyperhidrosis, Nickel allergy, Atopic dermatitis

Abstract

Background: Previously known as dyshidrosis, recurrent vesicular palmoplantar dermatitis (RVPD) is presented as severe eruption of non -erythematous, symmetrical vesicles or bullae located along the lateral sides of fingers, on the palmar or plantar areas, and developing into a chronic and recurrent condition. Although very frequently observed on the hands, there are no specific studies about such eczema in children and adolescents. Objectives of current study was to study clinical profile of RVPD in children and adolescents, and monitor the association of RVPD with seasonal variations, hyperhidrosis, atopy and nickel sulphate.

Methods: A cross sectional study was carried out in fifty patients affected by RVPD coming to out- patient department of dermatology in regional institute of medical sciences, Imphal, Manipur for a period of 24 months (October 2019 to September 2021) were collected using questionnaire. Data including age, sex, seasonal variation, hyperhidrosis, and atopy were collected. Relevant laboratory investigations like KOH examination, patch testing etc. were performed. Children (<12 years) and adolescents (13-18 years) irrespective of sex coming to opd were included and those unwilling to participate and treated elsewhere were excluded. Ethical approval was obtained from research ethics board and statistical analysis was done using IBM SPSS version 21.

Results: Majority (44%) of patients were in the age group 1-5 years. Hyperhidrosis (12%) was identified as second most contributing factor for RVPD after idiopathic cases. Atopy was the most common associated factor followed by seasonal warm weather exacerbation.

Conclusions: RVPD onset may occur at an early age, developing into a chronic and recurrent infection. Hyperhidrosis and atopic status was established in the clinical profile.

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References

Scotelaro HG, Fernandes NC, Ramos-e-Silva M. Clinical profile of recurrent vesicular palmoplantar dermatitis in children and adolescents. Clin Cos Invest Dermatol. 2019; 12(1):23-8.

Guillet MH, Wierzbicka E, Guillet S, Dagregorio G, Guillet G. A 3-year causative study of pompholyx in 120 patients. Arch Dermatol. 2007;143(12):1504-8.

Chen JJ, Liang YH, Zhou FS, Yang S, Wang J, Wang PG, et al. The gene for a rare autosomal dominant form of pompholyx maps to chromosome. J Invest Dermatol. 2006;126(2):300-4.

Lee CS, Lim HW. Cutaneous diseases in asians. Dermatol Clin. 2003;21(4):669-77.

Wollina U. Pompholyx. Am J Clin Dermatol. 2010; 11(5):305-14.

Nagarajan K, Thokchom NS, Ibochouba K, Verma K, Hafi NB. Pattern of paediatric dermatoses in Northeast India. IJPD. 2017;18(4):286.

Fox T. Clinical lecture on dysidrosis: an undescribed eruption. Br Med J. 1873;2(665):365.

Lodi A, Betti R, Chiarelli G, Urbani CE, Crosti C. Epidemiological, clinical and allergological observations on pompholyx. Contact Dermat. 1992;26(1):17-21.

Hutchinson J. Cheiro-Pompholyx. Br Med J. 1878; 1(889):54.

Agrup G. Hand eczema and other hand dermatoses in South Sweden. J Occup Environ Med. 1970;12(2):59.

Meneghini CL, Angelini G. Contact and microbial allergy in pompholyx. Contact Dermatitis. 1979; 5(1):46-50.

Jain VK, Aggarwal K, Passi S, Gupta S. Role of contact allergens in pompholyx. J Dermatol. 2004;31(3):188-93.

Christensen OB, Möller H. Nickel allergy and hand eczema. Contact Dermat. 1975;1(3):129-35.

Meding B, Swanbeck G. Epidemiology of different types of hand eczema in an industrial city. Acta Derm Venereol. 1989;69(3):227-33.

Lofgren SM, Warshaw EM. Dyshidrosis: epidemiology, clinical characteristics, and therapy. Dermatitis. 2006;17(4):165-81.

Weston JA, Hawkins K, Weston WL. Foot dermatitis in children. Paediatr. 1983;72(6):824-7.

Lehucher MP, Koeppel MC, Lanteaume A, Sayag J. Dyshidrotic eczema and occupation: a descriptive study. Contact Dermatitis. 2000;43(4):200-5.

Oddoze L, Temime P. Dyshidrosis and atopy. 2nd note: atopic component in dyshidrosis. Bull Soc Dermatol Syphiligr. 1968;75(3):378-80.

Agrup G. Hand eczema and other hand dermatoses in South Sweden. J Occup Environ Med. 1970;12(2):59.

Fredricks MG, Becker FT. Vesicular eruptions of the hands and feet of dyshidrotic type: clinical and therapeutical analysis. AMA Arch Derm Syphilol. 1954;70(1):107-14.