Multisystem Langerhans cell histiocystosis in a geriatric patient: case report

Diego M. Contreras; Grecia J. G. Gutiérrez; José M. Z. Torres; Félix O. Gutiérrez

doi:10.18203/issn.2455-4529.IntJResDermatol20221832

Authors

Diego M. Contreras Universidad de Sonora, Hermosillo, Sonora, México
Grecia J. G. Gutiérrez Hospital General Regional No. 1 Lic. Ignacio García Téllez, Mérida, México
José M. Z. Torres Universidad Autónoma de Guadalajara, Guadalajara, Jalisco, México http://orcid.org/0000-0002-1741-4117
Félix O. Gutiérrez Universidad Autónoma de Guadalajara, Guadalajara, Jalisco, México

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20221832

Keywords:

Histiocytosis, Langerhans cells, Langerhans cell histiocytosis in adults

Abstract

Langerhans cell histiocytosis is a condition of exceptional onset characterized by a proliferative event of dendritic cells with mono or multisystem involvement that predominates in the pediatric population and is identified in a smaller proportion in adults. It has a clinical impact and variable prognosis according to its location and number of organs affected. A 68-year-old male patient with clinical and immunohistochemical criteria for Langerhans cell histiocytosis with multisystem settlement with fatal outcome. It is a very rare disease, it is not exclusive to the pediatric population, with little understood pathogenesis and does not have specific treatment. In adults, the clinical impact is more aggressive, with a poorer prognosis and greater short-term complications.

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