Published: 2022-04-26

A cross-sectional study of cutaneous changes during pregnancy in a tertiary care hospital in Northern India

Azra Ferheen Chaudhary, Shitij Goel, Archana Mehta


Background: Women undergo profound changes during pregnancy, making them susceptible to a number of dermatological manifestations. We aimed to determine the frequency and pattern of skin changes during pregnancy.

Methods: A cross-sectional observational study was conducted among 400 pregnant women presenting to the Outpatient department of a Tertiary Care Centre in Northern India.

Results: A total of 400 pregnant mothers fulfilling inclusion criteria were included. The pigmentary changes were the most common physiological change seen in 90.8% (n=363) of pregnant women. The most common pigmentary change was secondary areola seen in 83% (n=332) women, followed by linea nigra seen in 37.5% (n=150) pregnant women. Vascular changes were seen in 13% (n=52), non- pitting pedal edema being the most common 10.25% (n=41). Connective tissue changes were seen in 62.25% (n=249) of pregnant women, striae gravidarum being the most common (n=242). The most common specific dermatoses of pregnancy was atopic eruption of pregnancy seen in 4.25% (n=17), followed by intrahepatic cholestasis of pregnancy (n= 14). 3 cases (0.75%) of Polymorphic eruption of pregnancy were seen. 1 case of Pemphigoid gestationis was seen in the third trimester. Approximately 17% of pregnant women were positive for infections among which fungal infection was the most common infection affecting pregnant women, seen in 11.2% (n=45) participants.

Conclusions: The dermatoses of pregnancy are common and have a range of dermatological manifestations apart from their specific pattern; in order to manage and treat them appropriately, proper attention needs to be given.


Dermatoses of pregnancy, Pigmentary changes, Dermatological manifestations

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Kroumpouzos G, Cohen LM. Dermatoses of pregnancy. J Am Acad Dermatol. 2001;45(1):1-22.

Heymann WR. Dermatoses of pregnancy update. J Am Acad Dermatol. 2005;52(5):888-9.

Rao PR, Rajamma A. Clinical Study of Cutaneous Manifestations in Pregnancy. IOSR J Dent Med Sci. 2019;18(1):24-30.

Dabette K, Bijayanti D, Hafi B, Singh R. Skin changes during pregnancy: A study from Northeast India. Indian Dermatol Online J. 2018;9(6):455-7.

Haritha K, Nataraj P. Study of skin changes and associated diseases in pregnancy. Int J Res Dermatology. 2018;4(4):586-90.

Muzaffar F, Hussain I, Haroon TS. Physiologic skin changes during pregnancy: A study of 140 cases. Int J Dermatol. 1998;37:429-31.

Ikram S, Malik A, Suhail M. Physiological skin changes during pregnancy. J Pakistan Assoc Dermatologists. 2018;28(2):219-23.

Panicker V V, Riyaz N, Balachandran PK. A clinical study of cutaneous changes in pregnancy. J Epidemiol Glob Health. 2017;7(1):63-70.

Kumari R, Jaisankar TJ, Thappa DM. A clinical study of skin changes in pregnancy. Indian J Dermatol Venereol Leprol. 2007;73(2):141.

Kannambal K, Tharini GK. A Screening Study on Dermatoses in Pregnancy. J Clin Diagn Res. 2017;11(5):WC01-5.

Puri N, Puri A. A study on dermatoses of pregnancy. Our Dermatol Online. 2013;4(1):56-60.