Hyperbaric oxygen therapy as an adjunctive treatment for pyoderma gangrenosum: a case report

Alan A. Katz; Kristin Thomson; Ursa Amin

doi:10.18203/issn.2455-4529.IntJResDermatol20214214

Authors

Alan A. Katz Hyperbaric Medical Solutions, Woodbury, NY http://orcid.org/0000-0002-2673-6265
Kristin Thomson Hyperbaric Medical Solutions, Woodbury, NY, USA; Department of Physician Assistant Studies, SUNY Stony Brook, NY, USA http://orcid.org/0000-0001-7208-4619
Ursa Amin Hyperbaric Medical Solutions, Woodbury, NY, USA

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20214214

Keywords:

Pyoderma gangrenosum, Hyperbaric oxygen therapy, Hyperbaric oxygenation, Refractory wounds

Abstract

Pyoderma gangrenosum is an uncommon inflammatory dermatosis associated with chronic wounds. Diagnosis and management can be challenging to clinicians due to the relapsing nature of the disorder, atypical presentations, and exclusion of other conditions before diagnosis. Hyperbaric oxygen therapy is not a mainstay of treatment for pyoderma gangrenosum, but it is used for non-healing wounds associated with diabetes and vascular insufficiency due to its primary mechanism of tissue hyperoxia, resultant angiogenesis, and reduction of edema and inflammation. This case report presents two patients with pyoderma gangrenosum who were provided adjunctive therapy with hyperbaric oxygen with favorable outcomes.

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