Clinical study of oral mucosal lesions in patients attending dermatology outpatient department in a tertiary care centre
Keywords:Oral mucosa, Oral lesions, Candidiasis
Background: Oral mucosa reflects the general health of an individual. In certain systemic diseases oral cavity may be affected first or it could the only clue to diagnosis. Hence skin examination is never complete without the examination of mucosae. Aims and objectives were to find out the frequency and diversity of oral mucosal lesions in patients attending Dermatology, Venereology and Leprosy (DVL) outpatient department (OPD).
Methods: This was a hospital based observational study. All patients with oral mucosal lesions fulfilling the inclusion &exclusion criteria were enrolled in the study. Detailed history, physical examination and clinical photographs were recorded for all the patients.
Results: The prevalence oral mucosal lesions among dermatological patients is 1.04% with a female predilection and the mean age was 38.44±17.30. Majority of the patients belonged to the age group of 31-60 years. Established risk factors for developing oral lesions like tobacco and beetle nut use was found in only 24% and 16% of the patients respectively. Twenty% (21%) of the patients were diabetic and the commonest oral lesions in them was oral candidiasis. Eighteen% (18%) of the patients presented with only oral complaints, while 82% of patients came with skin complaints and their oral lesions were incidental findings. Out of 82 patients with dermatological diseases specific mucocutaneous diseases were seen in 44% of patients. Most common dermatological diseases seen were vitiligo, lichen planus and pemphigus vulgaris.
Conclusions: Knowing the prevalence of oral lesions as a part of mucocutaneous disorders would help sensitise other specialities the need to examine oral cavity in order to attain appropriate and early diagnosis.
Babu RA, Chandrashekar P, Kumar KK. A Study on Oral Mucosal Lesions in 3500 Patients with Dermatological Diseases in South India. Ann Med Health Sci Res. 2014;4:84-93.
Thete SG, Kulkarni M, Nikam AP, Mantri T, Umbare D, Satdive S, Kulkarni D. Oral Manifestation in Patients diagnosed with Dermatological Diseases. J Contemp Dent Pract. 2017;18:1153-8.
Shivakumar KM, Kadashetti V, Chaudhary M, Swati Patil, Gawande M, Hande A. The Prevalence of Oral Mucosal Lesions in Patients with Dermatological Diseases Attending Tertiary Care Hospital in Central India. JKIMSU. 2017;6(3):55-61.
Roy S, Varshney S. Oral Dermatological Conditions: A Clinical Study. Indian J Otolaryngol Head Neck Surg. 2013;65:97-101.
Ramírez-Amador VA, Esquivel-Pedraza L, Orozco-Topete R. Frequency of oral conditions in a dermatology clinic. Int J Dermatol. 2000;39:501-5.
Gulati R, Nijhawan M, Agarwal S, Gupta I, Yadav S, Singh A, et al. Incidental Oral Mucosal findings in Outpatients Attending Dermatology Department in Outskirts of Jaipur: A Cross Sectional Observational Study. J Evol Med Dent Sci. 2015;4;6644-8.
Asia AJ, Ambade GR, Pagrut K. Oral Lesions in Patients Attending Dermatology and STD/HIV Outpatient Department: Analysis of A Cohort of 300 Cases. IOSR J Dent Med Sci. 2016;15:5-7.
Keswani T, Venkatraman S, Rathore BS, Nagaraju K, Goel S, Gupta S. Prevalence of oral mucosal lesions in dermatologically diseased patients: A cross-sectional study in Meerut. J Dent Res Rev. 2014;1:81-5.
Suliman NM, Åstrøm AN, Ali RW, Salman H, Johannessen AC. Oral mucosal lesions in skin diseased patients attending a dermatologic clinic: a cross-sectional study in Sudan. BMC Oral Health Lond. 2011;11:24.
Mishra SS, Kale LM, Sodhi SJ, Mishra PS, Mishra AS. Prevalence of oral premalignant lesions and conditions in patients with tobacco and tobacco-related habits reporting to a dental institution in Aurangabad. J Indian Acad Oral Med Radiol. 2014;26:152-7.
Ali M, Joseph B, Sundaram D. Ali M, Joseph B, Sundaram D. Prevalence of oral mucosal lesions in patients of the Kuwait University Dental Center. Saud Dent J. 2013;25(3):111-8.
Silva MFA, Barbosa KGN, Pereira JV, Bento PM, Godoy GP, Gomes DQ de C. Prevalence of oral mucosal lesions among patients with diabetes mellitus types 1 and 2. Anais Brasileiros de Dermatologia. 2015;90:49-53.
Vasconcelos BC, Novaes M, Sandrini FA, Maranhão AW, Filho, Coimbra LS. Prevalence of oral mucosa lesions in diabetic patients: a preliminary study. Braz J Otorhinolaryngol. 2008;74:423-8.
Al-Maweri SA, Ismail NM, Ismail AR, Al-Ghashm A. Prevalence of oral mucosal lesions in patients with type 2 diabetes attending hospital universiti sains malaysia. Malays J Med Sci. 2013;20(4):39-46.
Belazi M, Velegraki A, Fleva A, Gidarakou I, Papanaum L, Baka D, et al. Candidal overgrowth in diabetic patients: potential predisposing factors. Mycoses. 2005;48:192-6.
Shah H, Mehta A, Astik B. Clinical and sociodemographic study of vitiligo. Indian J Dermatol Venereol Leprol. 2008;74:701.
Goncalves LM, Bezerra JR, Junior, Cruz MC. Clinical evaluation of oral lesions associated with dermatologic diseases. An Bras Dermatol. 2010;85:150-6.
Mathew AL, Pai KM, Sholapurkar AA, Vengal M. The prevalence of oral mucosal lesions in patients visiting a dental school in Southern India. Indian J Dent Res. 2008;19:99-103.
Ikeda B, Ishii T, Iida S, Kawai T. Epidemiological study of oral leukoplakia based on mass screening for oral mucosal diseases in a selected Japanese population. Community Dent Oral Epidemiol. 1991;19:160-3.