DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20212790

Demographic profile of patients treated for melasma with glycolic acid and trichloroacetic acid: an institutional experience

Bikkasani U. P. Lakshmi Kishan Rao, K. Satyanarayana Rao

Abstract


Background: Melasma is an acquired disorder of hyperpigmentation characterised by forehead, cheeks, around eyelids and chin mostly in the sun-exposed areas of the skin. The etiology for melasma is not clear, various factors like genetic or hormonal influences the cause. The aim was to understand the demographical distribution and epidemiological pattern of pigmentation in melasma patients.

Methods: A total of 50 patients were participated in the present study at department of dermatology of Mamata medical college and hospital, Khammam over a period of one year.

Results: The mean age of patients with melasma was 33.84±5.76 years, with the youngest and oldest being 20 and 40 years with female preponderance, with a male to female ratio of 1:9. The maximum number of patients educated up to middle school level (38%) followed by primary school. The maximum number of individuals participated in the present study were housewife’s and out of 50 individuals 92% patients in the present series were married whereas family history of melasma was noted only 16% of the melasma patients.

Conclusions: The present observations demonstrates that the melasma is a female predominant, affecting young adults, etiological observations like sunlight, married, pregnancy, indoor, family history followed by cosmetics plays an important role in the melasma.


Keywords


Melasma, Demographical profile, MASI scoring, Glycolic acid and trichloroacetic acid

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References


Sarkar R, Arora P, Garg VK, Sonthalia S, Gokhale N. Melasma update. Indian Dermatol Online J. 2014;5(4):426-35.

Grimes PE. Melasma: etiologic and therapeutic consideration. Arch Dermatol. 1995;131(12):1453-7.

Lapeere H, Borne B, Schepper S, Verhaeghe E, Ongenae K, Geel NV. Hypomelanosis and hypermelanosis. In: Wolff K, Goldsmith LA, Katz SI, Gilchrest BA, Paller AS, Leffell DJ, eds. Dermatology in General Medicine. 7th ed. New York: McGraw-Hill; 2008: 622-40.

Yu RJ, Scott EJV. Bioavailability of alpha hydroxyl acids in topical formulations. Cosmetic Dermatol. 1996;9:54-6.

Brody H. History and classification of chemical peels. In: Patterson AN, eds. Chemical peeling. 1st ed. St. Louis: Mosby Book Inc; 1992: 7-22.

Finlay AY. 1997. Quality of life measurement in dermatology: a practical guide. Br J Dermatol. 1997;136(3):305-14.

Coleman WP, Futrell JM. The glycolic acid trichloroacetic acid peel. J Dermatol Surg Oncol. 1994;20(1):76-80.

Sanchez NP, Pathak MA, Sato S, Fitxpatrick TB, Snachez JL, Mihm MC. Melasma: A clinical, light microscopic, ultra-structural, and immunofluorescence study. J Am Acad Dermatol. 1981;4(6):698-710.

Patel NH, Gangaiah N, Thimappa V, Gundappa P. Clinico-epidemiological study of melasma in tertiary care centre. Int J Res Dermatol. 2020Jul;6(4):544-7.

Manjunath KG, Raghu MT, Yogendra M, Harish G. A clinical and therapeutic study of efficacy of 40% glycolic acid facial peels in melasma. Int J Res Dermatol. 2018;4(2):136-41.

Achar A, Rathi SK. Melasma: a clinic-epidemiological study of 312 cases. Indian J Dermatol. 2011;56(4):380-2.

Kalla G, Garg A, Kachhawa D. Chemical peeling: glycolic acid versus Trichloroacetic acid in melasma. Indian J Dermatol Venereol Leprol. 2001;67(2):82-4.

Javaheri SM, Handa S, Kaur I, Kumar B. Safety and efficacy of glycolic acid facial peel in Indian women with melasma. Int J Dermatol. 2001;40(5):354-7.

Sarkar R, Kaur C, Bhalla M, Kanwar AJ. The combination of glycolic acid peels with a topical regimen the treatment of Melasma in Dark skinned patients: a comparative study. Dermatol Surg. 2002;28(9):828-32.

Katsambas A, Soura E. Quality of life in melasma. Melasma and vitiligo in brown skin. 1st ed. New Delhi: Springer; 2017: 169-75.

Arora P, Meena N, Sharma PK, Raihan M. 2017. Impact of melasma on quality of life in Indian patients. Pigment Int. 2017;4(2):92.