Extensive erythema elevatum diutinum associated with IgA monoclonal gammopathy: a rare case report
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20212562Keywords:
Erythema elevatum diutinum, Extensive, IgA monoclonal gammopathyAbstract
Erythema elevatum diutinum (EED) is a rare form of leukocytoclastic vasculitis with an unclear pathogenesis. Almost 250 cases of EED have been reported in the literature, associated with several diseases and presented with various clinical features. Term 'diutinum' means chronic, describes one of the main characteristic features. The duration is very long, varying between one to more than 39 years. We report a rare presentation of EED in a 58-years-old man who presented with extensive and symmetrical, persistent, erythematous to violaceous plaques over trunk and limbs and popular-nodular lesions present over pinna and dorsum of hands with burning sensation and itching over few lesions, in association with IgA monoclonal gammopathy.
References
Cox NH, Jorizzo JL, Bourke JF, Savage COS. Vasculitis, neutrophilic dermatoses and related disorders. In: Burns T, Breathnach S, Cox N, Griffiths C, eds. Rook's Text Book of Dermatology. 8 th ed. Massachusetts, US: Blackwell Science; 2010: 25-27.
Wilkinson SM, English JS, Smith NP, Wilson JE, Winkelmann RK. Erythema elevatum diutinum: a clinicopathological study. Clin Exp Dermatol. 1992;17(2):87-93.
Ly H, Black MM. Atypical presentation of erythema elevatum diutinum. Australas J Dermatol. 2005;46(1):44-6.
Haber H. Erythema elevatum diutinum. Br J Dermatol. 1955;67(4):121-45.
Porneuf M, Duterque M, Sotto A, Jourdan J. Unusual erythema elevatum diutinum with fibrohistiocytic proliferation. Br J Dermatol. 1996;134(6):1131-4.
Devillierre M, Verola O, Rybojad M, Levy A, Vignon PMD, Morel P, et al. Pseudoneoplastic lesion of erythema elevatum diutinum. Ann Dermatol Venereol. 2008;135(8-9):575-9.
Gibson LE, Azhary RA. Erythema elevatum diutinum. Clin Dermatol. 2000;18(3):295-9.
Dronda F, Gonzalez LA, Lecona M, Barros C. Erythema elevatum diutinum in human immunodeficiency virus-infected patients--report of a case and review of the literature. Clin Exp Dermatol. 1996;21(3):222-5.
Archimandritis AJ, Fertakis A, Alegakis G, Bartsokas S, Melissinos K. Erythema elevatum diutinum and IgA myeloma: an interesting association. Br Med J. 1977;2(6087):613-4.
Yiannias JA, Azhary RA, Gibson LE. Erythema elevatum diutinum: a clinical and histopathologic study of 13 patients. J Am Acad Dermatol. 1992;26(1):38-44.
Momen SE, Jorizzo J, Niaimi F. Erythema elevatum diutinum: a review of presentation and treatment. J Eur Acad Dermatol Venereol. 2014;28(12):1594-602.
Grabbe J, Haas N, Moller A, Henz BM. Erythema elevatum diutinum-evidence for disease-dependent leucocyte alterations and response to dapsone. Br J Dermatol. 2000;143(2):415-20.
Rinard JR, Mahabir RC, Greene JF, Grothaus P. Successful surgical treatment of advanced erythema elevatum diutinum. Can J Plast Surg. 2010;18(1):28-30.
Statham BN, Greenwood R, Tring FC, Cotterill JA. Erythema elevatum diutinum--a report of two unusual patients. Clin Exp Dermatol. 1983;8(5):549-52.
