Eosinophilic cellulitis (wells syndrome): a case report
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20211708Keywords:
Eosinophilic cellulitis, Wells syndrome, Flame figuresAbstract
Eosinophilic Cellulitis is also known as Wells syndrome is uncommon dermatitis, characterized by the infiltration of eosinophils in the dermis. The exact etiology of the disease is unknown. Clinically, it is highly varied but commonly the presentation is pruritic erythematous plaque. We report a case of one and half years old healthy boy who developed itchy bullae on the dorsum of his hand with multiple erythematous papules over his extremities that started immediately after his vaccines. Histopathological examination of the lesion showed infiltrate eosinophils with typical flame figures. The case was successfully treated with corticosteroid course. This report aims to present a case of eosinophilic cellulitis (Wells syndrome) triggered by the vaccine with a literature review of the disease. In conclusion, atypical presentation of any inflammatory disorder or that not responding to appropriate treatment should trigger suspicion of eosinophilic cellulitis. Up to now, systemic corticosteroids are the most successful treatment of eosinophilic cellulitis.
Metrics
References
Almutlaga S. Eosinophilic Cellulitis (Wells Syndrome). Bahrain Medic Bullet. 2016;38(2):102-4.
Caputo R, Marzano AV, Vezzoli P, Lunardon L. Wells syndrome in adults and children: a report of 19 cases. Arch Dermatol. 2006;142(9):1157-61.
Safran T, Masckauchan M, Maj J, Green L. Wells syndrome secondary to influenza vaccination: A case report and review of the literature. Hum Vacc Immunotherap. 2018;14(4):958-60.
Wells G. Recurrent granulomatous dermatitis with eosinophilia. Transaction of the St. John's Hospit Dermatolog Soc. 1971;57(1):46-56.
Koutsalitis D, Karantoumanis D, Konstantinopoulos A, Pananaki A, Psomiadou M, Tzeli K, et al. P28-Wells’ syndrome (or Eosinophilic Cellulitis)–a case report. Clinic Translat All. 2014;4(1).
Sinno H, Lacroix JP, Lee J, Izadpanah A, Borsuk R, Watters K, et al. Diagnosis and management of eosinophilic cellulitis (Wells' syndrome): A case series and literature review. Canad J Plast Surg. 2012;20(2):91-7.
Herout S, Bauer WM, Schuster C, Stingl G. Eosinophilic cellulitis (Wells syndrome) successfully treated with mepolizumab. JAAD Case Rep. 2018;4(6):548.
Heelan K, Ryan JF, Shear NH, Egan CA. Wells syndrome (eosinophilic cellulitis): Proposed diagnostic criteria and a literature review of the drug-induced variant. J Dermatol Case Rep. 2013;7(4):113.
Räßler F, Lukacs J, Elsner P. Treatment of eosinophilic cellulitis (Wells syndrome)–a systematic review. J Europ Acad Dermatol Venereol. 2016;30(9):1465-79.
Downloads
Published
How to Cite
Issue
Section
