Familial median canaliform dystrophy of heller affecting multiple nails: a rare clinical entity
Keywords:Familial, Heller, Median canaliform dystrophy, Tacrolimus, Nail
Median canaliform dystrophy (MCD); first described by Heller in 1928 is characterized by a midline or paramedian split in the nail plate. Mostly idiopathic, some identifiable causes include habitual picking of the nails, oral isotretinoin use and positive family history. The familial occurrence of MCD has rarely been described. Till date, no therapy has proven to be consistently successful in effectively managing the condition. Commonly utilized treatments have been intralesional triamcinolone acetonide injections into the dystrophic nail, topical 0.1% tacrolimus ointment and topical tazarotene 0.05% ointment. Despite available treatment options, the condition has a tendency to recur. Here; we report a case of a 14‑year‑old male presenting with familial MCD affecting multiple finger and toe nails.
Heller J. Zur kasuistik seltener nagelkrankheiten: dystrophia unguium mediana canaliformis. Dermat Ztschr. 1928; 51:416-419.
Kim BY, Jin SP, Won CH, Cho S. Treatment of median canaliform nail dystrophy with topical 0.1% tacrolimus ointment. J Dermatol. 2010; 37:573‑4.
Griego RD, Orengo IF, Scher RK. Median nail dystrophy and habit tic deformity: Are they different forms of the same disorder? Int J Dermatol. 1995; 34:799‑800.
Bottomley WW, Cunliffe WJ. Median nail dystrophy associated with isotretinoin therapy. Br J Dermatol. 1992;127(4):447–48.
Dharmagunawardena B, Charles-Holmes R. Median canaliform dystrophy following isotretinoin therapy. Br J Dermatol. 1997;137(4):658–59.
Sweeney SA, Cohen PR, Schulze KE, Nelson BR. Familial median canaliform nail dystrophy. Cutis. 2005; 75:161‑5.
Rehtijarvi K. Dystrophia unguis mediana canaliformis. Acta Derm Venereol. 1971; 51:316-317.
Seller H. Dystrophia unguis mediana canaliformis. familial occurrence [in German]. Hautarzt. 1974; 25:456.
Bossi G. Heller’s dystrophia unguium mediana canaliformis [in Italian]. Minerva Dermatol. 1965; 40:303-04.
Grover C, Bansal S, Nanda S, Reddy BSN. Efficacy of triamcinolone acetonide in various acquired nail dystrophies. Journal of Dermatology. 2005;32(12):963–968.