A descriptive study of clinico-epidemiological profile of chronic urticaria from a tertiary care center

Authors

  • Olasseri Kalathingal Reena Mariyath Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India
  • Sreekanth Sukumarakurup Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India
  • Sanjayan Rosamma Roopasree Pinky Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India
  • Mohandas Ajina Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India
  • Kollarukandy Vijayan Anagha Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20210075

Keywords:

Chronic urticaria, Clinico-epidemiological, Descriptive study, Tertiary care center

Abstract

Background: Chronic urticaria is defined as wheals occurring at least twice weekly for more than six weeks. Exact etiology of chronic urticaria is not known. Only a few studies are available about the clinical and epidemiological profile of chronic urticaria from our part of the country.

Methods: A descriptive study was conducted among one hundred consecutives chronic urticaria patients attending the dermatology out patient department of government medical college, Kozhikode to find out the clinical and epidemiological profile of chronic urticaria.

Results: Out of 100 patients 25 (25%) were males and 75 (75%) were females with a male to female ratio of 1:3. Angioedema was seen in 63 (63%) patients and dermographism in 53 (53%) patients. Food was the aggravating factor in 34 (34%) patients, exposure to house dust in 28 (28%), sweat in 36 (36%), pressure in 37 (37%), sunlight in 17 (17%), drugs in 22 (22%), stress in 36 (36%), heat in 13 (13%), water in 20 (20%), cold in 5 (5%), infection in 31 (31%) and infestations in 20 (20%) patients.

Conclusions: Chronic urticaria is common in females. Angioedema and dermographism are seen in more than half of the patients with chronic urticaria. Most common aggravating factors of chronic urticaria were pressure, sweat, stress, food, infections and exposure to house dust.

Author Biographies

Olasseri Kalathingal Reena Mariyath, Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India

Associate Professor

Dept of Dermatology & Venereology

Sreekanth Sukumarakurup, Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India

Additional Professor

Dept of Dermatology & Venereology

Sanjayan Rosamma Roopasree Pinky, Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India

Junior resident

Dept of Dermatology & Venereology

Mohandas Ajina, Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India

Junior resident

Dept of Dermatology & Venereology

Kollarukandy Vijayan Anagha, Department of Dermatology and Venereology, Govt. Medical College, Kozhikode, Kerala, India

Junior resident

Dept of Dermatology & Venereology

References

Zuberbier T, Aberer W, Asero R, Bindslev-Jensen C, Brzoza Z, Canonica CW et al. The EAACI/GA (2) LEN/EDF/WAO guideline for the definition, classification, diagnosis and management of urticaria: the 2013 revision and update. Allergy. 2014;69:868-87.

Soter NA. Urticaria and angioedema. In: Fitzpatrick’s Dermatology in general medicine. Freedberg IM, Eisen AZ, Wolff K, et al, editors. 5th ed. New YORK: McGraw Hill. 1999;1049-25.

Ring J, Grosber M. Urticaria: Attempts at classification. Curr Allergy Asthma Rep. 2012;12(4):263-6.

Sabroe RA, Grattan CE, Francis DM, Barr RM, Black AK, Greaves MW. The autologous serum skin test: a screening test for autoantibodies in chronic idiopathic urticaria. Br J Dermatol. 1999;140(3):446-52.

Leznoff A, Sussman GL. Syndrome of idiopathic chronic urticaria and angioedema with thyroid autoimmunity: a study of 90 patients. J Allergy Clin Immunol. 1989;84(1):66-71.

Turktas I, Gokcora N, Demirsoy S, Cakir N, Onal E. The association of chronic urticaria and angioedema with autoimmune thyroiditis. Int J Dermatol. 2008;36(3):187-90.

Shankar DSK, Ramnane M, Rajouria EA. Etiological approach to chronic urticaria. Indian J Dermatol. 2010;55:33-8.

Gattey N, Bahrani B, Hull PR. Chronic Spontaneous Urticaria: A Questionnaire Survey. J Cutan Med Surg. 2016;20(3):241-3.

Heng JK, Koh LJ, Sim Toh MPH, Wee Aw DC. A study of treatment adherence and quality of life among adults with chronic urticaria in Singapore. Asia Pac Allergy. 2015;5(4);197-202.

Itakura A, Tani Y, Kaneko N, Hide M. Impact of chronic urticaria on quality of life and work in Japan: Results of a real-world study. J Dermatol. 2018;45(8):963-70.

Juhlin L. Recurrent urticaria: clinical investigation of 330 patients. Br J Dermatol. 1981;104(4):369-81.

Sibbald RG, Cheema AS, Lozinski A, Tario S. Chronic Urticaria: Evaluation of the role of physical, immunologic and other contributory factors. Int J Dermatol. 1991;30(6):381-6.

Curto-Barredo L, Archilla LR, Vives GR, Pujol RM, Gimenez-Arnau AM. Clinical Features of Chronic Spontaneous Urticaria that Predict Disease Prognosis and Refractoriness to Standard Treatment. Acta Derm Venereol. 2018;98(7):641-7.

Maurer M, Abuzakouk M, Berard F, Canonica W, Elberink HO, Gimenez-A rnau A et al. The burden of chronic spontaneous urticaria is substantial: Real-world evidence from ASSURE-CSU. Allergy. 2017;72(12):2005-16.

Kozel MM, Mekkes JR, Bossuyt PMM, Bos JD. Natural course of physical and chronic urticaria and angioedema in 220 patients. J Am Acad Dermatol. 2001;45(3);387-91.

Ojeda C, Vanegas E, Felix M, Mata V, Cherrez S, Simancas-Racines D et al. Etiology of chronic urticaria: the Ecuadorian experience. World Allergy Organ J. 2018;11(1):1.

Nettis E, Pannofino A, D’Aprile C, Ferrannini A, Tursi A. Clinical and aetiological aspects in urticaria and angio-edema. Br J Dermatol. 2003;148(3);501-6.

Kim BR, Yang S, Choi JW, Choi CW, Youn SW. Epidemiology and comorbidities of patients with chronic urticaria in Korea: A nationwide population-based study. J Dermatol. 2018;45(1):10-6.

Downloads

Published

2021-02-22

Issue

Section

Original Research Articles