Cutaneous manifestations of COVID-19: experience from a tertiary care center for COVID-19 management in South India
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20205606Keywords:
COVID-19, Cutaneous manifestations, Experience, South IndiaAbstract
Cutaneous manifestations observed in COVID-19 include maculopapular rash, urticaria, pseudo chilblain, vesicles, livedo reticularis, petechiae, erythema multiforme-like, symmetric drug related intertriginous and flexural exanthem (SDRIFE)-like and pityriasis rosea-like lesions. Maculopapular rash involving the trunk and sparing palms and soles is the most common cutaneous manifestation reported in COVID-19 patients. We report cutaneous manifestations in six COVID-19 patients from the corona isolation ward and intensive care unit of a tertiary care center for COVID-19 management in Kerala, South India. The skin lesions observed were urticaria (two patients), atypical maculopapular rash with urticarial and erythema multiforme-like lesions, eruptive pseudoangiomatosis, exaggerated insect bite reaction and acute localized exanthematous pustulosis (ALEP)-like lesions. To the best of our knowledge atypical maculopapular rash with urticarial and erythema multiforme-like lesions, eruptive pseudoangiomatosis and acute localized exanthematous pustulosis-like lesions are not reported in COVID-19.
Metrics
References
Zhu N, Zhang D, Wang, Li X, Yang B, Song J, et al. A novel corona virus from patients with pneumonia in China2019. N Engl J Med. 2020;382(8):727-33.
Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad. Dermatol Venereol. 2020;34(5):212-3.
Sachdeva M, Gianotti R, Shah M, Bradanini L, Tosi D, Veraldi S, et al. Cutaneous manifestations of COVID-19: Report of three cases and review of literature. J Dermatol Sci. 2020;98(2):75-81.
Galvan Casas C, Catala A, Hernandez GC, Rodriguez-Jimenez P, Fernandez-Nieto D, Lario RA, et al. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Br J Dermatol. 2020;183(1):71-7.
Wollina U, Karadag AS, Rowland-Payne C, Chiriac A, Lotti T. Cutaneous signs in COVID-19 patients: A review. Dermatol Ther. 2020;33(5).
Mariyath OK, Samad KA, Devi K, Surya VS, Effeena MD, Ajina M. Atypical maculopapular rash as the initial sign of COVID-19: A case report from a COVID hospital. J Skin Sex Transm Dis. 2020.
Algaadi SA. Urticaria & COVID-19: A review. Dermatol Ther.2020;14290.
Jimenez-Cauhe J, Ortega-Quijano D, Carretero-Barrio I, Suarez-Valle A, Saceda-Corralo D, Moreno-Garcia del Real et al. Erythema multiforme like eruption in patients with COVID-19 infection: clinical and histological findings. Clin Exp Dermatol. 2020;45(7).
Robustelli Test E, Vezzoli P, Carugno A, Raponi F, Gianatti A, Rongioletti F, et al. Acute generalized exanthematous pustulosis with erythema multiforme like lesions induced by Hydroxychloroquine in a woman with coronavirus disease 2019 (COVID-19). J Eur Acad Dermatol Venereol. 2020;34(9).
Neri I, Patrizi A, Guerrini V, Ricci G, Cevenini R. Eruptive pseudoangiomatosis. Br J Dermatol. 2020;143(2):435-8.
Kaya G, Lang C. A Case of Adrenergic Urticaria Associated with Vitiligo. Dermatopathology. 2016;3:83-6.
Cherry JD, Bobinski JE, Horwath FL, Comerci GD. Acute hemangioma like lesions associated with echoviral infections. Paediatrics.1961;44:498-502.
Gianotti R, Zerbi P, Dodiuk-Gad RP. Clinical and histopathological study of skin dermatoses in patients affected by COVID-19 infection in the Northern part of Italy. J Cosmet Dermatol Sci. 2020;98(2):141-3.
Wang D, Tang H, Shen Y, Wang F, Lin J, Xu J. Activation of the blood coagulation system in patients with chronic spontaneous urticria. Clin Lab. 2015;61:1283-8.
Ucmak D, Akkurt M, Toprak G, Yesilova Y, Turan E, Yildiz I. Determination of dermatology life quality index and serum C-reactive protein and plasma IL-6 levels in patients with chronic urticaria. Postepy Dermatol Allergol. 2013;30:146-51.
Lazzaroni MG, Piantoni S, Masneri S, Garrafa E, Martini G, Tincani A, et al. Coagulation dysfunction in COVID-19: The interplay between inflammation, viral infection and the coagulation system. Blood Rev. 2020;100745.