DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20204569

Langerhans cell histiocytosis in an infant: a case report from North-East India

Romita Bachaspatimayum, Kago Yaku

Abstract


Langerhans cell histiocytosis (LCH) is a rare disorder of reticuloendothelial system characterized by uncontrolled proliferation and accumulation of CD1a and CD207 dendritic cells (DCs). 3-4 cases per million occur annually in children under 15 years of age, with a male:female ratio of 2:1 and peak incidence in infants aged 1 to 2 years. Report a case of LCH in a month-old female infant with skin lesions for 2-3 weeks. Skin biopsy was suggestive of LCH and it was confirmed with immunohistochemistry markers that were positive for S100, CD1A and negative for CD68.

 


Keywords


Children, Cutaneous manifestations, LCH

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References


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