Bacteriological and antibiotic susceptibility study of pyodermas at a tertiary care center in central Karnataka
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20170804Keywords:
Pyoderma, Staphylococcus aureus, Antibiotic susceptibility, Antibiotic resistanceAbstract
Background: Pyoderma is defined as a skin infection mainly caused by Staphylococcus aureus, Streptococcus pyogenes or both. Pyoderma is a common skin infection in India and constitutes major portion of patients in dermatological clinics. Many cases nowadays do not respond to the antibiotics that were previously sensitive. In order to successfully treat cases of pyodermas, sound knowledge is necessary regarding the etiology and their sensitivity patterns. Objectives of this study were to determine clinico-epidemiological and etiological factors associated in patients with pyoderma and to find sensitivity pattern of isolated organisms to various antibiotics commonly used.
Methods: A hospital based cross sectional study was performed on 100 patients presenting with bacterial skin infections to the Dermatology out-patient department of a tertiary care centre in Central Karnataka. Clinical and epidemiological features were recorded on a predefined proforma. Sterile swabs were used to collect the pus from the lesions under aseptic precaution. Antimicrobial susceptibility testing of the isolated strains to different groups of drugs was tested on Muller Hinton agar by the Kirby Bauer disc diffusion method.
Results: Primary pyodermas was seen more in the age group of 21-30 years (21%), followed by 31-40 years (19%). Folliculitis (32%) was the commonest clinical type followed by furuncles (28%). Among the gram positive isolates, Vancomycin (88.24%), Linezolid (86.67%) and Cefoxitin (71%) were the most susceptible drugs, whereas Amoxicillin (92.86%) and penicillin G (88.37%) were the most resistant drugs.
Conclusions: Pyodermas have been the major cause of morbidity since long. Even though pyoderma is a common condition, emerging multidrug resistant strains is of major concern to treat these conditions. Suitable and judicious selection of antibiotics by using antibiotic sensitivity data would limit the emerging drug resistant strains in the future to treat these clinical conditions successfully.
References
Janak K, Singh OP, Usha G. Bacteriology of pyoderma including anaerobes. Indian J Med Res. 1989;89:261-4.
Pasricha A, Bhujwala RA, Shriniwas A. Bacteriological study of pyoderma. Indian J Pathol Bacteriol. 1972;15:131-8.
Bhawani Y, Ramani TV, Sudhakar VA. Bacteriological study of 100 cases of superficial pustular folliculitis with special reference to Staphylococci from lesions and carrier sites Biology and Medicine. 2011;3(4):7-12.
Tan HH, Tay YK, Gho CL. Bacterial Skin Infections at a Tertiary Dermatological Centre. Singapore Med J. 1998;39(8):353-6.
Bhaskaran CS, Rao PS, Krishnamurthy T, Tarachand P. Bacteriological study of pyoderma. Indian J DermatolVenereolLeprol. 1971;45(3):162-9.
Jayaraj YM, Kulkarni V, Shivannavar CT, Arali SM, Ravi M. Clinico-Bacteriological studies on pyoderma in Gulbarga region (Karnataka state) emphases to Methicillin Resistant Staphylococcus aureus. Int J Pharm Bio Sci. 2014;5(1):616-24.
Ghadage DP, Sali YA. Bacteriological study of pyoderma with special reference to antibiotic susceptibility to newer antibiotics. Indian J Dermatol Venereol Leprol. 1999;65:177-81.
Singh A, Gupta LK, Khare AK, Mittal A, Kuldeep CM, Balai M. A clinico-bacteriological study of pyodermas at a tertiary health center in southwest Rajasthan. Indian J Dermatol. 2015;60:479-84
Patil R, Baveja S, Nataraj G, Khopkar U. Prevalence of methicillin - resistant Staphylococcus aureus (MRSA) in community-acquired primary pyoderma. Indian J Dermatol Venereol. 2006;72:126–228.
Nagmoti MJ, Patil CS, Metgud SC. A bacterial study of pyoderma in Belgaum. Indian J Dermatol Venereol Leprol. 1999;65:69-71.
Gandhi S, Ojha AK, Ranjan KP, Neelima. Clinical and bacteriological aspects of pyoderma: An overview. N Am J Med Sci. 2012;4(10):492-5.
Baslas RG, Arora SK, Mukhija RD, Mohan L, Singh UK. Organisms causing pyoderma and their susceptibility patterns. Indian J Dermatol Venereol Leprol. 1990;56:127-9.
Mendiratta PL, Vidhani S, Mathur MD. A study on staphylococcus aureus strains submitted to a reference laboratory. Indian J Med Res. 2001;114:90-4.
