Cutaneous metastasis of signet ring cell appendiceal adenocarcinoma: a herald of disease recurrence
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20201588Keywords:
Metastatic signet ring cell appendiceal adenocarcinoma, Cutaneous metastasis, Signet ring cell, Appendiceal adenocarcinomaAbstract
Signet ring cell appendiceal adenocarcinoma (SRCAA) is a rare entity with poor prognosis and high tendency for metastasis to pelvic lymph nodes, ovaries, and peritoneal surfaces. Despite numerous reports of intra-abdominal metastasis, there have been few reported cases of cutaneous SRCAA metastasis. We report a rare case of SRCAA metastatic to the cutaneous abdominal wall in a 67 years old female, which was first presenting sign of disease recurrence.
Metrics
References
Fusari M, Sorrentino N, Bottazzi EC. Primary signet ring cell carcinoma of the appendix mimicking acute appendicitis. Acta Radiol Short Reports. 2012;1(9):1-3.
Ruoff C, Hanna L, Zhi W, Shahzad G, Gotlieb V, Saif MW. Cancers of the Appendix: Review of the Literatures. ISRN Oncol. 2011;2011:1-6.
Ko YH, Jung CK, Oh SN. Primary signet ring cell carcinoma of the appendix: a rare case report and our 18-year experience. World J Gastroenterol. 2008;14(37):5763-8.
Wang HL, Dhall D. Goblet or Signet Ring Cells. Adv Anat Pathol. 2009;16(4):247-54.
Bertuzzo VR, Coccolini F, Pinna AD. Peritoneal seeding from appendiceal carcinoma: A case report and review of the literature. World J Gastrointest Surg. 2010;2(8):265.
Ploenes T, Borner N, Kirkpatrick CJ, Heintz A. Neuroendocrine Tumour, Mucinous Adenocarcinoma and Signet-Ring Cell Carcinoma of the Appendix: Three Cases and Review of Literature. Indian J Surg. 2013;75(S1):299-302.
Connor SJ, Hanna GB, Frizelle FA. Appendiceal tumors: retrospective clinicopathologic analysis of appendiceal tumors from 7,970 appendectomies. Dis Colon Rectum. 1998;41(1):75-80.
Donnell OME, Badger SA, Beattie GC, Carson J, Garstin WIH. Malignant neoplasms of the appendix. Int J Colorectal Dis. 2007;22(10):1239-48.
Diffuse gastric cancer/Genetic and Rare Diseases Information Center (GARD) - an NCATS Program. Available at: https://rarediseases.info.nih.gov/ diseases/10334/disease. Accessed November 12, 2018.
Muta H, Noguchi M, Kanai Y, Ochiai A, Nawata H, Hirohashi S. E-Cadherin Gene Mutations in Signet Ring Cell Carcinoma of the Stomach. Japanese J Cancer Res. 1996;87(8):843-8.
Nakatsuru S, Yanagisawa A, Ichii S. Somatic mutation of the APC gene in gastric cancer: frequent mutations in very well differentiated adenocarcinoma and signet-ring cell carcinoma. Hum Mol Genet. 1992;1(8):559-63.
Pathology Outlines - Signet ring cell carcinoma. http://www.pathologyoutlines.com/topic/colontumorsignetring.html. Accessed November 12, 2018.
Goldblum JR, Hart WR. Perianal Paget’s disease: a histologic and immunohistochemical study of 11 cases with and without associated rectal adenocarcinoma. Am J Surg Pathol. 1998;22(2):170-9.
Rosen Y, Kim B, Yermakov VA. Eccrine sweat gland tumor of clear cell origin involving the eyelids. Cancer. 1975;36(3):1034-41.
Kuno Y, Numata T, Kanzaki T. Adenocarcinoma with signet ring cells of the axilla showing apocrine features: a case report. Am J Dermatopathol. 1999;21(1):37-41.
Kiyohara T, Kumakiri M, Kouraba S, Tokuriki A, Ansai S. Primary cutaneous signet ring cell carcinoma expressing cytokeratin 20 immunoreactivity. J Am Acad Dermatol. 2006;54(3):532-6.
Kim HJ, Ha HK, Cho KS. CT features of primary colorectal signet-ring cell carcinoma. J Comput Assist Tomogr. 2001;25(2):225-30.
Chu PG, Weiss LM. Immunohistochemical Characterization of Signet-Ring Cell Carcinomas of the Stomach, Breast, and Colon. Am J Clin Pathol. 2004;121(6):884-92.
Nonaka D, Kusamura S, Baratti D, Casali P, Younan R, Deraco M. CDX-2 expression in pseudomyxoma peritonei: a clinicopathological study of 42 cases. Histopathology. 2006;49(4):381-7.
Zhou M, Yan F, Xu P, Zhang L, Li Q, Ji Y. Mucinous cystadenoma of the appendix: CT findings. Chin Med J (Engl). 2006;119(15):1300-3.
Cusker MME, Cote TR, Clegg LX, Sobin LH. Primary malignant neoplasms of the appendix. Cancer. 2002;94(12):3307-12.