Evaluation of vitamin D status, selenium and C-reactive protein level in psoriasis

Authors

  • S. Sumathi Department of Biochemistry, Mahatma Gandhi Medical College and Research Institute, Pillaiyarkuppam, Puducherry, India
  • S. Vinod Babu Department of Biochemistry, Mahatma Gandhi Medical College and Research Institute, Pillaiyarkuppam, Puducherry, India
  • K. Karthikeyan Department of Dermatology, Sri Manakula Vinayagar Medical College and Hospital, Madagadipet, Puducherry, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20195681

Keywords:

C-reactive protein, Vitamin-D, Psoriasis, Selenium

Abstract

Background: Psoriasis is an inflammatory skin disease associated with a variety of clinical conditions. Study aim to evaluate the association of vitamin D, selenium and C-reactive protein (CRP) levels in psoriasis.

Methods: This hospital-based case-control study involved 50 psoriasis cases and 47 healthy individuals. Serum vitamin D, selenium and CRP levels were measured, and the general demographic values were also recorded.

Results: Statistical analysis revealed that vitamin D levels are significantly lower in psoriasis (p<0.005). Among the demographic parameters, obesity was found more common among psoriasis cases than controls. Serum selenium and CRP levels were not significantly different between the two groups.

Conclusions: Vitamin D deficiency is strongly associated with psoriasis. Vitamin D supplementation can be useful in psoriasis management and also in the reduction of obesity. Serum selenium and CRP levels aren’t significant markers to demonstrate psoriasis.

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Published

2019-12-23

Issue

Vol. 6 No. 1 (2020): January-February 2020

Section

Original Research Articles