Toxic epidermal necrolysis treated with filgrastim and dexamethasone

Authors

  • Nishant Choudhary Department of Dermatology, L.N. Medical College and Research Centre, Bhopal, Madhya Pradesh,
  • Nidhi Sharma Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal
  • Sujata Sinha Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal
  • Sudip Das Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20193122

Keywords:

Toxic epidermal necrolysis, Filgrastim

Abstract

We report a case of 22 year female with toxic epidermal necrolysis while on carbamazepine. One hospital outside treated her with steroids but she didn’t show any improvement and rather worsened. The patient reported to us with fluctuating blood pressure and dyselectrolytemia. Patient also developed neutropenia (3,200/mm3) and sepsis. Patient was treated with filgrastim and dexamethasone. Filgrastim was added because of neutropenia and earlier case reports suggesting it aid in faster healing. Patient made a complete recovery. 

Author Biographies

Nishant Choudhary, Department of Dermatology, L.N. Medical College and Research Centre, Bhopal, Madhya Pradesh,

Assistant Professor,Department of Dermatology

Nidhi Sharma, Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal

Senior Resident, Department of Dermatology, CNMC

Sujata Sinha, Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal

Junior Resident, Department of Dermatology,CNMC

Sudip Das, Department of Dermatology, Calcutta National Medical College, Kolkata, West Bengal

Professor, Department of Dermatology,CNMC

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Published

2019-07-24