DOI: http://dx.doi.org/10.18203/issn.2455-4529.IntJResDermatol20163976

Epidemiological study, clinical spectrum and associations of childhood vitiligo in a tertiary care centre

Rangaraj Murugaiyan

Abstract


Background: Childhood vitiligo is a special subtype and is seen in significant proportion of vitiligo patients. There are only a few clinical studies in the past which address the clinical spectrum of vitiligo in children. This study on eighty cases of childhood vitiligo will cover the epidemiology and clinical spectrum.

Methods: To study the epidemiology, clinical spectrum and associations in childhood vitiligo. Inclusion criteria: all new cases of vitiligo in children under 12 years attending the outpatient department of Dermatology, exclusion criteria: old treated cases of vitiligo and age more than 12 years. Statistical analysis was done using mean and percentage of means.

Results: Most common age group affected includes 4-6 years. Most common site of initial lesion was head and neck followed by upper limb, lower limb and trunk. Most common clinical type was vitiligo vulgaris followed by focal type then segmental. Lip tip type was least common type.

Conclusions: Childhood vitiligo is a serious issue and the knowledge of its various patterns and associations needs to be updated at regular intervals.


Keywords


Hypothyroidism, Autoimmune, Leucotrichia

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References


Dhar S, Dutta P, Malakar R. Vitiligo, pigmentary disorders; IADVL textbook of dermatology. Volume 1. Chapter 25. 3rd edition. Mumbai: Bhalani publishing house; 2010: 749-760.

Handa S, Dogra S. Epidemiology of childhood vitiligo: a study of 625 patients from north India. Pediatr Dermatol. 2003;20(3):207-10.

Mosher DB, OrtonneJP, Fitzpatrick TB. Disorder of pigmentation. In: Fitzpatrick’s TB, Eisen AZ, Wolff K , et al editors. Dermatology in General medicine. 3rd edition. New York: Mc Graw Hill; 1987: 794-876.

Chandra S, Kumar A, Singh KK, Mohan L. Congenital vitiligo. Indian J Dermatol Venereol Leprol. 1992;58:339.

Kanwar AL, Dhar S, Kaur S. Vitiligo in children. Ind J Dermatol.1993;38:47-52.

Lerner AB. Vitiligo. J Invest Dermatol. 1959;32:285-310.

Lerner AB. On the etiology of Vitiligo and gray hair. Am J Med. 1971:51:141-7.

Bystryn JC. Theories on the pathogenesis of Depigmentation: Immune hypothesis. In: SK Hann, JJ Nordlund, editors. Vitiligo. London: Blackwell science; 2000: 129.

Das PK, René MJGJ, van den Wijngaard, Wankowicz-Kalinska A, Caroline Le Poole I. A Symbiotic concept of autoimmunity and tumour immunity: Lessons from vitiligo. Trends Immunol. 2001;22:130.

Le Poole IC, Das PK, van den Wijngaard RM, Bos JD, Westerhof W. Review of etiopathomechanism of vitiligo: A Convergence theory. Exp Dermatol. 1993;2:145.

Boissy RE. The intrinsic (genetic theory) for the cause of Vitiligo. In: SK Hann, JJ Nordlund, editors. Vitiligo. London: Blackwell science; 2000: 123.

Nordlund JJ. Vitiligo: A review of some facts lesser known about depigmentation. Indian J Dermatol. 2011;56:180-9.

Sarin KC, Kumar AS. A clinical study of vitiligo. Indian J Dermatol Venereol Leprol. 1977;43:311-4.

Handa S, Kaur I. Vitiligo: Clinical findings in 1436 patients. J Dermatol. 1999;26:653-7.

Jaishankar TJ, Baruah MC, Garg BR. Vitiligo in children. Int J Dermatol. 1992;31:621-3.

Belliappa PR, Priya KS, Umashankar N, Vivekananda, Lokanath L. Characteristics of Childhood Vitiligo in Bangalore with special reference to associated Ocular abnormalities. e-J Indian Soc Teledermatol. 2011;4(3):1-10.

Hu Z, Liu JB, Ma SS, Yang S, Zhang XJ. Profile of childhood vitiligo in China: An analysis of 541 patients. Pediatr Dermatol. 2006;23:114–6.