Prevalence of HIV in syphilis in a tertiary care centre

Authors

  • Sumithra Sundararaj Department of Dermatovenereology and Leprosy, Government Rajaji Hospital, Madurai Medical College, Madurai, Tamilnadu
  • Devaprabha Sendurpandian Department of Dermatovenereology and Leprosy, Government Rajaji Hospital, Madurai Medical College, Madurai, Tamilnadu
  • Suganthy R. Rajakumari Department of Dermatovenereology and Leprosy, Government Rajaji Hospital, Madurai Medical College, Madurai, Tamilnadu

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20191768

Keywords:

Syphilis, HIV, Seroprevalence

Abstract

Background: Aim of this study was to determine the prevalence of HIV in syphilis in patients attending the STD clinic in a tertiary care center.

Methods: Study was conducted in all new patients attending the STD clinic during the study period of 6 months from June 2012 to November 2012. Clinically suspected cases of syphilis were diagnosed serologically and all the patients were tested for HIV after proper counselling and consent.

Results: In a total of 200 new patients attended the STD clinic 47 (23.5%) were diagnosed as syphilis. Majority of the cases (43) were latent syphilis in our study. A total of 77 (38.5%) cases were reactive to HIV. Among the 47 (23.5%) syphilis cases 24 (51%) were reactive to HIV. In the age group of 21-30 years most of the syphilis male (5/6) patients showed HIV reactivity.

Conclusions: Seroprevalence of syphilis among other STI was found to be significant. Rising trend in latent syphilis was noted may be due to antenatal checkup, purpose of foreign job and strict blood screening protocols. The prevalence of HIV in syphilis individual was 51% and it was high in the age group of 31-50 when compared to other age group. In the age group of 21-30 most of the males, diagnosed as syphilis were serologically positive for HIV. Hence these sexually active groups were to be targeted for their safe sexual practice to prevent the transmission of HIV.

References

Nair TG, Asha LK, Leelakumari PV. An epidemiological study of sexually transmitted diseases. Indian J Dermatol Venereol Leprol. 2000;66:69-72.

Nair BKH, Viswam MP, Venugopal BS, Nair PS. An epidemiological study of venereal diseases. Indian J Med Res. 1973;61:1697-707.

Gregory N, Sanchez M, Buchness MR. The spectrum of syphilis in patients with human immunodeficiency virus infection. J Am Academy Dermatol. 1990;22(6):1061-75.

Carlson JA, Dabiri G, Cribier B, Sell S. The immunopathobiology of syphilis: the manifestations and course of syphilis are determined by the level of delayed-type hypersensitivity. Am J dermatopathol. 2011;33(5):433.

Saikia L, Nath R, Deuori T, Mahanta J. Sexually transmitted diseases in Assam: An experience in a tertiary care referral hospital. Indian J Dermatol Venereol Leprol. 2009;75(3):329.

Gawande AV, Vasudeo ND, Zodpey SP, Khandait DW. Sexually transmitted infections in long distance truck drivers J Commun Dis. 2000;32(3):212-5.

Ray K, Bala M, Gupta SM, Khunger N, Puri P, Muralidhar S, et al. Changing trends in sexually transmitted infections at a Regional STD Centre in North India. Indian J Med Res. 2006;124:559–68.

Maity S, Bhunia SC, Biswas S, Saha MK. Syphilis seroprevalence among patients attending a sexually transmitted disease clinic in West Bengal, India. Jpn J Infect Dis. 2011;64:506–8.

Thakur TS, Sharma V, Goyal A, Gupta ML. Seroprevalence of HIV antibodies, Australia antigen and VDRL reactivity in Himachal Pradesh. Indian J Med Sci. 1991;45:332–5.

Olokoba AB, Olokoba LB, Salawu FK, Danburam A, Desalu OO, Badung LH, et al. Syphilis in voluntary blood donors in North-eastern Nigeria Eur J Sci Res. 2009;31(3):335-40.

AM Baião, E Kupek, A PetrySyphilis seroprevalence estimates of Santa Catarina blood donors in 2010 Rev Soc Bras Med Trop, 47 (2) (2014), pp. 179-185

Eyaufe AA, Osagie RN, Isibor JO, Okwu GI, Oriakhi RE, Turay AA. Performance of syphilis serology in students of Ambrose Alli University, Ekpoma, Nigeria. Int J Med Med Sci. 2009;1(4):138-9.

Tankhiwale SS, Naikwade SR. Seroprevalence of syphilis and biologically false positive cases in a tertiary care center. Indian J Dermatol Venereol Leprol. 2014;80 (4):340-1.

Nishal PK, Kapoor A, Jain VK, Dayal S, Aggarwal K. Changing trends in acquired syphilis at a Tertiary Care Center of North India. Indian J Sex Transm Dis 2015; 36: 149-53

Mutagoma M, Remera E, Sebuhoro D, Kanters S, Riedel DJ, Nsanzimana S. The prevalence of syphilis infection and its associated factors in the general population of Rwanda: A National Household-Based Survey. J sexually transmitted dis. 2016;2016:1-8.

Jayasree P, Binitha MP, Najeeba R, Biju G. Clinical and epidemiological profile of sexually transmitted infections in a tertiary care centre in Kerala: A 1-year observational study. Indian J Dermatol Venereol Leprol. 2015;81:500-3.

Heffelfinger JD, Swint EB, Berman SM, Weinstock HS. Trends in primary and secondary syphilis among men who have sex with men in the United States. Am j public health. 2007;97(6):1076-83.

Balaji AB, Bowles KE, Le BC, Paz-Bailey G, Oster AM. High HIV incidence and prevalence and associated factors among young MSM, 2008. AIDS. 2013;27(2):269.

Garg T, Chander R, Jain A, Barara M. Sexually transmitted diseases among men who have sex with men: A retrospective analysis from Suraksha clinic in a tertiary care hospital. Indian j sexually transmitted dis. 2012;33(1):16.

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Published

2019-04-26

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Original Research Articles