Studying the clinic mycological pattern of the dermatophytic infection attending OPD in tertiary care hospital in eastern Uttar Pradesh and Bihar
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20180987Keywords:
Dermatophytosis, Superficial mycoses, Tinea, Trichophyton spp, Microsporum sppAbstract
Background: Superficial dermatophytic infection is infection of skin nail or hair with fungus. Nowadays, these fungal infection are at a rise and run a prolong course despite of treatment due to resistance to conventional antifungal agents. There is a felt need to conduct epidemiological study to know the change in the pattern and cause of widespread resistance. This study was aimed at identifying clinico-mycological pattern of dermatophytic infections in patients attending the dermatology outpatient department of a tertiary care hospital in eastern Uttar Pradesh and adjoining area.
Methods: Patients with suspected dermatophytoses attending the outpatient department were enrolled in the study. A detailed history, clinical examination and sample collection for mycological examinations was done.
Results: There were 500 patients recruited in the study, with a male: female ratio of 3:1. The most commonly affected age group was 20–30 years (35%). Tinea corporis et cruris was the most common type observed (31%). Potassium hydroxide positivity was seen in 390 samples (78%) and culture positivity was found in 350 samples (70%). The most common species identified was Trichophyton verrucosum (35.5%).
Conclusions: There is a rise in dermatophytic infection caused by zoophilic species like Trichophyton verrucousum.
Metrics
References
Patel P, Mulla S, Patel D, Shrimali GS. A Study of superficial mycosis in south Gujarat region. National J Community Med. 2010;1:85-8.
Singh S. Beena PM. Profile of Dermatophytes infection in Baroda. IJDVL. 2003;69:281-3.
Das K, Basak S, Ray S. A Study on Superficial fungal infection from west Bengal: A brief report. J Life Sci. 2009;1:51-5.
Grove S, Roy P. Clinico- mycological Profile of Superficial mycosis in a Hospital in North East India. MJAFI. 2003;59:114-9.
Bindu V. Clinico Mycological study of dermatophytosis in Calicut. IJDVL. 2002;68:259-61.
Gopi A, Harindranath D, Kaushik AR. Mycological profile of dermatophytes isolated from clinical samples in KIMS hospital, Bangalore. J Evol Med Dent Sci. 2015;4:835-42.
Patel P, Mulla S, Patel D, Shrimali G. A study of superficial mycosis in South Gujarat region. Natl J Community Med. 2010;1:85-8.
Sumana V, Singaracharya MA. Dermatophytosis in Khammam (Khammam district, Andhra Pradesh, India). Indian J Pathol Microbiol. 2004;47:287-9.
Kumar Y, Singh K, Kanodia S, Singh S, Yadav N. Clinico-epidemiological profile of superficial fungal infections in Rajasthan. MedPulse-Int Med J. 2015;2:139-43.
Kumar S, Mallya PS, Kumari P. Clinico-mycological study of dermatophytosis in a tertiary care hospital. Int J Sci Study. 2014;1:27-32.
Kamothi MN, Patel BP, Mehta SJ, Kikani KM, Pandhya JM. Prevalence of dermatophyte infection in district Rajkot. Electron J Pharmacol Ther. 2010;3:1-3.
Bindu V, Pavithran K. Clinico-mycological study of dermatophytosis in Calicut. Indian J Dermatol Venereol Leprol. 2002;68:259-61.
Sahai S, Mishra D. Change in spectrum of dermatophytes isolated from superficial mycoses cases: First report from Central India. Indian J Dermatol Venereol Leprol. 2011;77:335-6.
Prabhu SR, Shetty VH, Shetty NJ, Girish PN, Rao BP, Oommen RA, et al. Clinico-mycological study of superficial fungal infections in coastal Karnataka, India. J Evol Med Dent Sci. 2013;2:8638-46.
Asadi MA, Dehghani R, Sharif MR. Epidemiologic study of onychomycosis and tinea pedis in Kashan, Iran. Jundishapur J Microbiol. 2009;2:61-4.
Madhavi S, Rama Rao MV, Jyothsna K. Mycological study of dermatophytosis in rural population. Ann Biol Res. 2011;2:88-93.
Lyngdoh CJ, Lyngdoh WV, Chohury B, Sangma KA, Bora I, Khyriem AB. Clinico-mycological profile of dermatophytosis in Meghalaya. Int J Med Public Health. 2013;3:254-6.
Bhagra S, Ganju SA, Kanga A, Sharma NL, Guleria RC. Mycological pattern of dermatophytosis in and around shimla hills. Indian J Dermatol. 2014;59:268-70.
Sarma S, Borthakur AK. A clinico-epidemiological study of dermatophytoses in Northeast India. Indian J Dermatol Venereol Leprol. 2007;73:427-8.
Gupta S, Gupta BL. Evaluation of the incidences of dermatophillic infection in Rajasthan: Case studies from Rajasthan, India. Int J Med Med Sci. 2013;5:229-32.
Surekha A, Ramesh Kumar G, Sridevi K, Murty DS, Usha G, Bharathi G. Superficial dermatomycoses: A prospective clinicomycological study. J Clin Sci Res. 2015;4:7-15.
Jain N, Sharma M, Saxena VN. Clinico-mycological profile of dermatophytosis in Jaipur, Rajasthan. Indian J Dermatol Venereol Leprol. 2008;74:274-5.
Aggarwal A, Arora U, Khanna S. Clinical and mycological study of superficial mycoses in Amritsar. Indian J Dermatol. 2002;47:218-20.
Malik A, Fatima N, Khan PA. A clinico-mycological study of superficial mycoses from a tertiary care hospital of a North Indian town. Virol Mycol. 2014;3:135.
Sen SS, Rasul ES. Dermatophytosis in Assam. Indian J Med Microbiol 2006;24:77-8.
Sumana MN, Rajagopal V. A study of dermatophytes and their in-vitro antifungal sensitivity. Indian J Pathol Microbiol. 2002;45:169-72.
Garg J, Tilak R, Garg A, Prakash P, Gulati AK, Nath G. Rapid detection of dermatophytes from skin and hair. BMC Res Notes. 2009;2:60.
Levitt JO, Levitt BH, Akhavan A, Yanofsky H. The sensitivity and specificity of potassium hydroxide smear and fungal culture relative to clinical assessment in the evaluation of tinea pedis: A pooled analysis. Dermatol Res Pract. 2010;2010:764843.
Shenoy MM, Teerthanath S, Karnaker VK, Girisha BS, Krishna Prasad MS, Pinto J. Comparison of potassium hydroxide mount and mycological culture with histopathologic examination using periodic acid-Schiff staining of the nail clippings in the diagnosis of onychomycosis. Indian J Dermatol Venereol Leprol. 2008;74:226-9.
Ecemis T, Degerli K, Aktas E, Teker A, Ozbakkaloglu B. The necessity of culture for the diagnosis of tinea pedis. Am J Med Sci. 2006;331:88-90.
Bhatia VK, Sharma PC. Epidemiological studies on Dermatophytosis in human patients in Himachal Pradesh, India. Springerplus. 2014;3:134.
Kaviarasan PK, Jaisankar TJ, Thappa DM, Sujatha S Clinical variations in dermatophytes in HIV infected patients. Indian J Dermatol Venereol Leprol. 2002;68:213-6.
Ellabib MS, Khalifa ZM Dermatophytes and other Fungi Associated with skin mycosis in Tripoli. Libya.Ann Saud Med. 2001;21:193-6.
Hay RJ, Moore M, Champion RH, Burton JL, Burns DA, et al. Text book of dermatology 6th ed. Oxford Blackwell Science Ltd; 1998: 1277-1377.
Greer DL Evolving role of non dermatophytes in onchomycosis. Int J Dermatol. 1995;34:52-9.
Vinod S, Grover S, Dash K, Singh G. A clinico- Mycological evaluation of onchomycosis. Ind J Dermatol Venereol Leprol. 2000;66:238-40.
English MP. Nail and Fungi. Br J Dermatol. 1976;94:697-701.