Clinical profile, etiology and histopathology of patients with erythroderma in South India
DOI:
https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20173919Keywords:
Erythema, Scaling, Inflammation, Skin biopsyAbstract
Background: Erythroderma is a generalised inflammatory disorder of skin manifesting with erythema and scaling affecting more than 90% of the skin surface. Several studies have highlighted the importance of biopsy in the diagnosis and management of erythroderma, while some others have found it to be of limited use.
Methods: Thirty-six patients with erythroderma were enrolled in the study and a detailed history, clinical examination and relevant investigations including skin biopsy was done to find out the etiology.
Results: Pre-existing dermatoses were the predominant cause (84%) contributed equally by psoriasis (42%) and eczemas (42%) and clinicopathologic correlation could be obtained in 30.55% of cases.
Conclusions: Our study showed that skin biopsy remains a valuable tool in the diagnosis of erythroderma.
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References
Walsh NMG, Prokopetz R, Tron VA. Histopathology in erythroderma: review of a series of cases by multiple observers. J Cutan Pathol. 1994;21:419-23.
Sigurdson V,Toonstra J, Hengemann, Boer M. A clinical and follow up study of 102 patients of erythroderma with special emphasis on survival. J Am Acad Dermatol.1996;35:53-7.
Sigurdsson V, Steegmans PHA, van Vloten WA. The incidence of erythroderma:a survey among all dermatologists in The Netherlands. J Am Acad Dermatol. 2001;45:675-8.
Bostella-Estrada R, Sanmartin O, Oliver V. Erythroderma- a clinicopathological study of 56 cases. Arch Dermatol. 1994;130:1503-7.
Rothe MJ, Bernstein ML, Grant-Kels JM:Life-threatening erythroderma: diagnosing and treating the "red man". Clin Dermatol. 2005;23:206-17.
Khaled A, Sellami A, Fazaa B, Kharfi M, Zeglaoui F, Kamoun MR. Acqiured erythroderma in adults:a clinical and prognostic study. J Eur Acad Dermatol Venereol. 2010;24:781-8.
Farideh Jowker, Fatemeh Sari Aslani,Maryam Shafiee. Erythroderma: a clinicopathological study of 102 cases. J Pakistan Assoc Dermatol. 2006;16:129-33.
Maryam Akhyani, Zahra S Ghodsi. Erythroderma:A clinical study of 97 cases. BMC Dermatol. 2005;5:1471-5.
Pal S, Haroon TS. Erythroderma: A clinicoetiological study of 90 cases. Int J Dermatol. 1998;37:104-7.
Wong KS. Generalised exfoliative dermatitis-A clinical study of 108 patients. Ann Acad Med Singapore. 1988;17:520.
Sehgal VN, Srivastava G. Exfoliative dermatitis-a prospective study of 80 Patients. Dermatologica. 1986;173:278-84.
Nicolis GD, Helwig EB. Exfoliative dermatitis. A clinicopathological study of 135 cases. Arch Dermatol.1973;108:788-97.
King LE Jr, Dufresne RG Jr, Lowelt GL. Erythroderma-review of 82 cases. South Med J. 1986;79:1210-5.
Bostella-Estrada R, Sanmartin O, Oliver V. Erythroderma- a clinicopathological study of 56 cases. Arch Dermatol. 1994;130:1503-7.
Abrahams I, Mc Carthy Jt, Sanders SL. 101 cases of exfoliative dermatitis. Arch Dermatol.1963;87:96-101.
Wilson HTH. Exfoliative dermatitis:its etiology and prognosis. Arch Dermatol. 1954;69:577-88.
Gentele H, Lodin A, Skog E. Dermatitis exfoliativa. Acta Derm Venereol (Stockh). 1958;38:296-302.
Abrahams I, Mc Carthy Jt,Sanders SL.101 cases of exfoliative dermatitis. Arch Dermatol. 1963;87:96-101.
Nicolis GD, Helwig EB. Exfoliative dermatitis. A clinicopathological study of 135 cases. Arch Dermatol. 1973;108:788-97.
Ndiaye B, Sissoko F, Strobel M. Les erythrodermies de l'adulte. Dakar Med. 1979;24:65-74.
Hasan T, Jansen CT. Erythroderma: a follow up of 50 cases. J Am Acad Dermatol. 1983;8:836-40.