Published: 2022-08-25

Cutaneous manifestations of COVID-19: a case report and review of the literature

Jose Luis Martinez Arismendi, Jose Maria Zepeda Torres, Felix Osuna Gutierrez, Laura Fischert Melendez, Grecia Jazmín Gutiérrez García, Paola Lizette Padilla


Since the onset of the SARS-Cov2 pandemic, new data and peculiarities have emerged within the range of manifestations caused by this virus. Multisystem inflammatory syndrome in children (MIS-C) affects a small percentage of pediatric patients infected with SARS CoV 2 and characterized by fever, lab evidence of inflammation, multisystem involvement, and severe illness requiring hospitalization. Cutaneous findings are often present in these patients and are notable for their heterogeneity and poor characterization. We present case of pediatric patient with COVID-19 and cutaneous manifestations consistent with a multisystem inflammatory syndrome.


Skin, Manifestations, COVID-19, Case report

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Rothan HA, Byrareddy SN. The potential threat of multisystem inflammatory syndrome in children during the COVID-19 pandemic. Pediatr Allergy Immunol. 2021;32(1):17-22.

Rafferty MS, Burrows H, Joseph JP, Leveille J, Nihtianova S, Amirian ES. Multisystem inflammatory syndrome in children (MIS-C) and the coronavirus pandemic: Current knowledge and implications for public health. J Infect Public Health. 2021;14(4):484-94.

Feldstein LR, Rose EB, Horwitz SM. Multisystem Inflammatory Syndrome in U.S. Children and Adolescents. N Eng J Med. 2020;383(4):334-46.

Leidman E, Duca LM, Omura JD, Proia K, Stephens JW, Sauber-Schatz EK. COVID-19 Trends Among Persons Aged 0-24 Years - United States. 2020. MMWR Morbidity and Mortality Weekly Report. 2021;70(3):88-94.

Brumfiel CM, DiLorenzo AM, Petronic-Rosic VM. Dermatologic manifestations of COVID-19-associated multisystem inflammatory syndrome in children. Clin Dermatol. 2021;39(2):329-33.

Hoang A, Chorath K, Moreira A. COVID-19 in 7780 pediatric patients: A systematic review. E-Clin Med. 2020;24.

Genovese G, Moltrasio C, Berti E, Marzano AV. Skin Manifestations Associated with COVID-19: Current Knowledge and Future Perspectives. Dermatology. 2021;237(1):1-12.

Galván Casas C, Català A, Carretero Hernández G. Classification of the cutaneous manifestations of COVID-19: a rapid prospective nationwide consensus study in Spain with 375 cases. Bri JZ Dermatol. 2020;183(1):71-7.

Askin O, Altunkalem RN, Altinisik DD, Uzuncakmak TK, Tursen U, Kutlubay Z. Cutaneous manifestations in hospitalized patients diagnosed as COVID-19. Dermatologic Therapy. 2020;33(6).

Morey-Olivé M, Espiau M, Mercadal-Hally M, Lera-Carballo E, García-Patos V. Cutaneous manifestations in the current pandemic of coronavirus infection disease (COVID 2019). Anales de Pediatría. 2020;92(6):374-5.

Athwani V, Gothwal S. Dermatological Manifestations of COVID-19 in Children. J Skin Stem Cell. 2020;7:2.

Andina D, Belloni-Fortina A, Bodemer C. Skin manifestations of COVID-19 in children: Part 3. Clin Exp Dermatol. 2021;46(3):462-72.

Ludvigsson JF. Systematic review of COVID-19 in children shows milder cases and a better prognosis than adults. Acta Paediatr. 2020;109(6):1088-95.

Torrelo A, Andina D, Santonja C. Erythema multiforme-like lesions in children and COVID-19. Pediatr Dermatol. 2020;37(3):442-6.

Mirza FN, Malik AA, Omer SB, Sethi A. Dermatologic manifestations of COVID-19: a comprehensive systematic review. Int J Dermatol. 2021;60(4):418-50.

Welsh EC, Alfaro Sanchez AB, Ortega Gutiérrez GL. COVID-19 dermatological manifestations: results from the Mexican Academy of Dermatology COVID-19 registry. Int J Dermatol. 2021;60(7):879.