The prevalence of metabolic syndrome in male patients of early onset androgenic alopecia compared to age matched controls

Authors

  • Nitin D. Chaudhari Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Chandrakant B. Poulkar Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Swapna S. Khatu Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Gaurav H. Khandait Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Rajvardhan M. Bagane Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Abhishek S. Patokar Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Chinmay M. Ratkanthiwar Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India
  • Supriya S. Pathade Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India

DOI:

https://doi.org/10.18203/issn.2455-4529.IntJResDermatol20214824

Keywords:

Androgenetic alopecia, Metabolic syndrome, Diastolic blood pressure, Trichoscopy

Abstract

Background: Androgenic alopecia is most common type of non-scarring alopecia in men. It is associated with high risk of cardiovascular events. Aim was to study the prevalence of metabolic syndrome in male patients of early onset androgenic alopecia.

Methods: A case-control study was conducted at the dermatology out-patient department over a period of 6 months which included 100 patients of androgenic alopecia and 100 age matched controls. All subjects were aged 20 to 35 years and underwent detailed history, clinical examination including trichoscopic examination and measurement of waist circumference and blood pressure. Fasting blood sugar, triglyceride and high-density lipoproteins were tested following overnight fasting. Diagnosis of metabolic syndrome was based on criteria of national cholesterol education program (NCEP) adult treatment panel III. Chi square test was used as a test of significance. P value <0.05 was considered statistically significant.

Results: Prevalence of metabolic syndrome was more in androgenic alopecia patients than in controls (48% versus 18%, p value <0.001). Androgenic alopecia patients had higher prevalence of increased waist circumference (76% versus 28%, p value <0.0001), increased diastolic blood pressure (32% versus 12%, p value=0.007), increased serum triglycerides (46% versus 24%, p value=0.0011) and decreased serum high-density lipoproteins (36% versus 18%, p value=0.0042) compared to controls.

Conclusions: Early screening for metabolic syndrome and its components is beneficial in patients with androgenic alopecia to reduce cardiovascular mortality.

Author Biography

Chandrakant B. Poulkar, Smt. Kashibai Navale Medical College and General Hospital, Pune, Maharashtra, India

Associate Professor, Department of dermatology,venereology and leprosy

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Published

2021-12-24

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Original Research Articles