Published: 2021-06-24

Hair: more than just an appendage

Harshitha Reddy, Srikanth Shanmugam, Manobalan Karunanandhan


Hypotrichosis is a relatively common feature of a number of complex hereditary syndromes. However, the isolated variant, called hereditary hypotrichosis simplex (HHS), is uncommon. We present a 4 years old child and his father who presented to us with features suggestive of HHS. No other associated ectodermal and systemic abnormalities were noted.


Hypotrichosis, Hereditary hypotrichosis simplex, Ectodermal defects, Trichoscopy

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Cruz CF, Costa C, Gomes AC, Matamá T, Cavaco-Paulo A. Human Hair and the Impact of Cosmetic Procedures: A Review on Cleansing and Shape-Modulating Cosmetics. Cosmetics. 2016;3(3):20-6.

Koslu A, Ekmekci TR, Cetincelik U. A case of hereditary hypotrichosis simplex. J Eur Acad Dermatol Venereol. 2006;20(9):1150-1.

Pasricha JS, D’Souza P. Topical fluocinolone acetonide acetate ointment in autosomal dominant congenital hypotrichosis. Indian J Dermatol Venereol Leprol. 1996;62(4):242-5.

Farah RS, Holahan HM, Moye MS, Stone MS, Swick BL. Hereditary Hypotrichosis Simplex of the Scalp. 2017;100(1):12-4.

Moravvej-Farshi H, Ayatollahi A, Hejazi S. Hereditary hypotrichosis simplex of the scalp. Indian J Dermatol. 2014;59(6):634.

Li M, Cheng R, Zhuang Y, Yao Z. A recurrent mutation in the APCDD1 gene responsible for hereditary hypotrichosis simplex in a large Chinese family. Br J Dermatol. 2012;167(4):952-4.

Vázquez MR, Rodríguez RR, Tapia AG, Diez LI. Hereditary Hypotrichosis Simplex of the Scalp. Pediatr Dermatol. 2002;19(2):148-50.